A Comprehensive Update of the Superior Hypogastric Block for the Management of Chronic Pelvic Pain

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This review synthesizes evidence on the superior hypogastric plexus block, an interventional technique that provides long-lasting pain relief for many patients with chronic pelvic pain, regardless of procedural approach.

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This paper is a comprehensive review of the superior hypogastric (superior hypogastric plexus) block as an interventional option for chronic pelvic pain, outlining definitions, epidemiology, diagnostic approach, etiologies, and available treatments, with attention to evidence on the block’s efficacy. It reports that chronic pelvic pain commonly affects reproductive-aged women, is often associated with endometriosis (among other causes), is clinically diagnosed, and is frequently underdiagnosed; the review states that superior hypogastric plexus block has been associated with long-lasting pain relief in about 50–70% of patients across differing image-guidance approaches (fluoroscopy, ultrasound, CT). A key limitation explicitly noted is that evidence quality/level is limited and further randomized controlled trials are needed for better evaluation and patient selection. This paper is centrally about endometriosis — it specifically frames chronic pelvic pain pathophysiology as being often endometriosis (70%), and it discusses superior hypogastric plexus block as a potential interventional treatment within that broader endometriosis-containing clinical context.

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Abstract

PURPOSE OF REVIEW: This is a comprehensive review of the superior hypogastric block for the management of chronic pelvic pain. It reviews the background, including etiology, epidemiology, and current treatment available for chronic pelvic pain. It then presents the superior hypogastric block and reviews the seminal and most recent evidence about its use in chronic pelvic pain. RECENT FINDINGS: Several definitions exist for chronic pelvic pain (CPP), making the diagnosis more challenging for the clinician; however, they commonly describe continuous pain lasting 6 months in the pelvis, with an overwhelming majority of patients being reproductive-aged women. This pain is often one of mechanical, inflammatory, or neuropathic. It is generally underdiagnosed and affects anywhere between 5 and 26% of women. The diagnosis of chronic pelvic pain is clinical, consisting of mainly of a thorough history and physical and ruling out other causes. The pathophysiology is often endometriosis (70%) and also includes PID, adhesions, adenomyosis, uterine fibroids, chronic processes of the GI and urinary tracts, as well as pelvic-intrinsic musculoskeletal causes. Treatment includes physical therapy, cognitive behavioral therapy, and oral and parenteral opioids. Interventional techniques provide an added tier of treatment and may help to reduce the requirement for chronic opioid use. Superior hypogastric plexus block is one of the available interventional techniques; first described in 1990, it has been shown to provide long-lasting relief in 50-70% of patients who underwent the procedure. Two approaches described so far, both under fluoroscopy, have seen similar results. More recently, ultrasound and CT-guided procedures have also been described with similar success. The injectate includes local anesthetic, steroids, and neurolytic agents such as phenol or ethanol. CPP is a common debilitating condition. It is diagnosed clinically and is underdiagnosed globally. Current treatments can be helpful at times but may fall short of satisfactory pain relief. Interventional techniques provide an added layer of treatment as well as reduce the requirement for opioids. Superior hypogastric plexus block provides long-lasting relief in many patients, regardless of approach. Evidence level is limited, and further RCTs could help provide better tools for evaluation and patient selection.
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Abstract

Purpose of Review This is a comprehensive review of the superior hypogastric block for the management of chronic pelvic pain. It reviews the background, including etiology, epidemiology, and current treatment available for chronic pelvic pain. It then presents the superior hypogastric block and reviews the seminal and most recent evidence about its use in chronic pelvic pain. Recent Findings Several definitions exist for chronic pelvic pain (CPP), making the diagnosis more challenging for the clinician; however, they commonly describe continuous pain lasting 6 months in the pelvis, with an overwhelming majority of patients being reproductive-aged women. This pain is often one of mechanical, inflammatory, or neuropathic. It is generally underdiagnosed and affects anywhere between 5 and 26% of women. The diagnosis of chronic pelvic pain is clinical, consisting of mainly of a thorough history and physical and ruling out other causes. The pathophysiology is often endometriosis (70%) and also includes PID, adhesions, adenomyosis, uterine fibroids, chronic processes of the GI and urinary tracts, as well as pelvic-intrinsic musculoskeletal causes. Treatment includes physical therapy, cognitive behavioral therapy, and oral and parenteral opioids. Interventional techniques provide an added tier of treatment and may help to reduce the requirement for chronic opioid use. Superior hypogastric plexus block is one of the available interventional techniques; first described in 1990, it has been shown to provide long-lasting relief in 50–70% of patients who underwent the procedure. Two approaches described so far, both under fluoroscopy, have seen similar results. More recently, ultrasound and CT-guided procedures have also been described with similar success. The injectate includes local anesthetic, steroids, and neurolytic agents such as phenol or ethanol. Summary CPP is a common debilitating condition. It is diagnosed clinically and is underdiagnosed globally. Current treatments can be helpful at times but may fall short of satisfactory pain relief. Interventional techniques provide an added layer of treatment as well as reduce the requirement for opioids. Superior hypogastric plexus block provides long-lasting relief in many patients, regardless of approach. Evidence level is limited, and further RCTs could help provide better tools for evaluation and patient selection. Similar content being viewed by others

References

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Management of cyclical pelvic pain by multiple ultrasound-guided superior hypogastric plexus blocks in a rare case of Mayer-Rokitansky-Küster-Hauser syndrome - a case series of three blocks in a patient. Intractable Rare Dis Res. 2019;8(4):271–4. Author information Authors and Affiliations Corresponding author Ethics declarations Conflict of Interest Ivan Urits, Ruben Schwartz, Jared Herman, Amnon A. Berger, David Lee, Alec M Zamarripa, Annabel Slovek, Laxmaiah Manchikanti, and Omar Viswanath declare no conflict of interest. Alan Kaye is a Section Editor for Current Headache and Pain Reports. He has not been involved in the editorial handling of this manuscript. Dr. Kaye is also a speaker for Merck. Human and Animal Rights and Informed Consent This article does not contain any studies with human or animal subjects performed by any of the authors. Additional information Publisher’s Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This article is part of the Topical Collection on Chronic Pain Medicine Rights and permissions About this article Cite this article Urits, I., Schwartz, R., Herman, J. et al. A Comprehensive Update of the Superior Hypogastric Block for the Management of Chronic Pelvic Pain. Curr Pain Headache Rep 25, 13 (2021). https://doi.org/10.1007/s11916-020-00933-0 Accepted: Published: Version of record: DOI: https://doi.org/10.1007/s11916-020-00933-0

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endometriosischronic_pelvic_painadenomyosis

MeSH descriptors

Autonomic Nerve Block Chronic Pain Chronic Pain Hypogastric Plexus Pain Management Pelvic Pain Pelvic Pain Analgesics, Opioid Analgesics, Opioid Anesthetics, Local Anesthetics, Local Autonomic Nerve Block Chronic Pain Chronic Pain Endometriosis Endometriosis Endometriosis Endometriosis Female Humans

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