A Sign of Disparity: Racial/Ethnic Composition of Treatment Centers is an Independent Risk Factor in SPRINT Trial

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Abstract

The racial composition of treatment centers in the SPRINT trial is an independent risk factor for myocardial infarction (MI) and stroke. Independent of individual race or ethnicity, patients face a 39% increase in relative risk of MI or stroke when associated to treatment centers with a high proportion of African Americans. The magnitude of this effect is comparable to smoking. This suggests the strong influence of social determinants on health outcomes among hypertensive patients.

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europepmc
last seen: 2026-05-19T01:45:01.086888+00:00