SULFONYLATED HETEROCYCLES USEFUL FOR MODULATION OF THE PROGESTERONE RECEPTOR

MCCOMAS CASEY CAMERON, FENSOME ANDREW
2008
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This patent describes sulfonylated heterocycles that modulate the progesterone receptor for treating or preventing endometriosis, uterine leiomyomata, and other hormone-dependent conditions.

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Abstract

Compounds of the following structure are provided, wherein R1-R4 and R6-R9 are defined below, as are methods of preparing and using these compounds for contraception; treating or preventing fibroids, uterine leiomyomata, endometriosis, dysfunctional bleeding, polycystic ovary syndrome, and hormone-dependent carcinomas; providing hormone replacement therapy; stimulating food intake; synchronizing estrus; and treating cycle-related symptoms.

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europepmc
last seen: 2026-10-26T06:15:05.866214+00:00