Effects of PKF 115–584 on cell migration and invasion.

A, B: Number of migrated cells/mm2 in non-treated and PKF 115–584–treated endometrial epithelial (A) and stromal (B) cells of patients with and without endometriosis. C, D: Number of invasive cells/mm2 in non-treated and PKF 115–584–treated endometrial epithelial (C) and stromal (D) cells of patients with and without endometriosis. Results are presented as the mean+SEM. M: menstrual phase, P: proliferative phase, S: secretory phase. Endo (+): Endometrium of patients with endometriosis (M: n = 4, P: n = 8, S: n = 8). Endo (–): endometrium of patients without endometriosis (M: n = 4, P: n = 5, S: n = 5). a: p<.05 versus PKF 115–584–treated endometrial epithelial or stromal cells of patients without endometriosis.