The effect of reducing the negative monetary externality of muscle injuries in professional football: evidence from the implementation of prevention methods. | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article The effect of reducing the negative monetary externality of muscle injuries in professional football: evidence from the implementation of prevention methods. DANIEL MEGIA-CAYUELA This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-8377147/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Muscle injuries represent a major concern in professional football, generating significant financial losses due to player downtime, medical expenses, and reduced performance. Integrating physiogenomics, individualized training, and personalized nutrition offers a promising strategy to reduce injury incidence and improve team efficiency. This study evaluated the effectiveness of physiogenomic profiling combined with tailored nutritional programs in preventing muscle injuries and enhancing performance in professional football players, while estimating economic benefits for clubs. A predictive model based on previous studies estimated injury risk according to genotypes (RR, RX, XX). Personalized nutritional interventions were implemented during the 2024/25 season, with longitudinal monitoring of biochemical markers, injury incidence, and physical performance. Players with the XX genotype showed a notable decrease in injury frequency and severity, along with reductions in creatine kinase levels. Economic modelling estimated annual savings of €5 million per club in LaLiga and €11 million in the Premier League. JEL Codes: I12, I18, I15, L83, Q18, M54 monetary externality muscle injury costs prevention methods predictive modeling sports economics Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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