The follow-up visit and observation of adenomyosis treated with Mirena

Airong Shen, Yifan Feng, Xiang Gao, Jie Li, Fang Wang
In: Central Plains Medical Journal · 2013 · vol. 40(11) , pp. 23–24 · doi:10.3760/cma.j.issn.1674-4756.2013.11.009 · W3032537463
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Levonorgestrel-releasing intrauterine (Mirena) treatment of adenomyosis significantly reduced dysmenorrhea, menstrual volume, and endometrial thickness, with minor side effects.

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This study evaluated the clinical efficacy and adverse effects of the levonorgestrel-releasing intrauterine system, commonly known as Mirena, in managing adenomyosis. Researchers followed fifty-three patients at a university hospital, tracking changes in dysmenorrhea scores, menstrual volume, endometrial thickness, and uterine size at one, three, and six months post-insertion. The results demonstrated statistically significant reductions in pain and bleeding, along with decreased endometrial thickness, although the reduction in uterine volume was not statistically significant. Common side effects included irregular vaginal spotting, menopausal symptoms, vaginal dryness, and osteoporosis. This paper is centrally about adenomyosis — specifically the use of a levonorgestrel-releasing intrauterine device for symptom management and disease modification.

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Abstract

Objective To investigate the clinical effect and sides effects of levonorgestrel-releasing intrauterine(Mirena) in the treatment of adenomyosis.Methods Fifty-three cases of adenomyosis treated with levonorgestrel-releasing intrauterine system in the third affiliated hospital of Zhengzhou university during August 2010 and April 2012 were followed-up.The change of dysmenorrhea and menstrual volume,sides effects before and after 1,3,6 months insertion respectively were observed.Results The grades of both postoperative dysmenorrhea,menstrual volume and endometrial thickness markedly decreased,with statistical significance (P ＜ 0.01).The uterine volume slightly reduced,but there was no statistical significant differece before and after treatment (P ＞ 0.05).The main side effects were little vaginal bleeding,menopausal symptom,colpoxerosis,osteoporosis and so on.Conclusions Mirena was an effective method in the treatment of adenomyosis. Key words: Levonorgestrel-releasing intrauterine ;  Adenomyosis ;  Follow-up
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摘要目的 探讨左炔诺孕酮宫内缓释系统(LNG-IUS,商业名曼月乐)治疗子宫腺肌病的临床疗效及不良反应.方法 随访2010年8月至2012年4月期间在郑州大学第三附属医院门诊就诊的宫内放置曼月乐环的53例患有子宫腺肌病患者,观察曼月乐环放置前及放置后的1、3、6个月的痛经评分、PBAC月经量评分、子宫体积及内膜厚度等多项改变及使用曼月乐环后相关的不良反应.结果 曼月乐治疗前后患者痛经症状显著减轻(P＜0.01),月经量显著减少(P＜0.01),子宫内膜变薄(P＜0.01)；子宫体积稍有缩小,但差异无统计学意义(P＞0.05).伴随阴道不规则点滴出血、围绝经期症状、阴道干燥、骨质疏松等不良反应.结论 左炔诺孕酮宫内缓释系统是治疗子宫腺肌病的一种有效治疗方法. 更多相关知识 abstractsObjective To investigate the clinical effect and sides effects of levonorgestrel-releasing intrauterine(Mirena) in the treatment of adenomyosis.Methods Fifty-three cases of adenomyosis treated with levonorgestrel-releasing intrauterine system in the third affiliated hospital of Zhengzhou university during August 2010 and April 2012 were followed-up.The change of dysmenorrhea and menstrual volume,sides effects before and after 1,3,6 months insertion respectively were observed.Results The grades of both postoperative dysmenorrhea,menstrual volume and endometrial thickness markedly decreased,with statistical significance (P ＜ 0.01).The uterine volume slightly reduced,but there was no statistical significant differece before and after treatment (P ＞ 0.05).The main side effects were little vaginal bleeding,menopausal symptom,colpoxerosis,osteoporosis and so on.Conclusions Mirena was an effective method in the treatment of adenomyosis. More相关知识 - 浏览314 - 被引8 - 下载189 相似文献 - 中文期刊 - 外文期刊 - 学位论文 - 会议论文

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