MMP-2、TIMP-2与子宫腺肌病相关性研究的进展
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Abstract
子宫腺肌病（adenomyosis,AM）是子宫内膜向肌层良性浸润并在其中弥漫性生长所发生的一种妇科疾病。其主要临床表现有月经量多、经期延长、继发性痛经渐进性加重等,严重影响妇女的生活质量[1]。MMPs及其抑制剂TIMPs在AM的发生发展中发挥着重要作用,尤其MMP-2和TIMP-2是一组与子宫内膜细胞侵袭性密切相关的指标,AM中MMP-2和TIMP-2平衡的打破是AM进展的重要因素之一。因此,随着对MMPs、TIMPs与AM发生发展关系的进一步研究,有望研制出相关的新药,将会给AM的治疗带来极为广阔的前景。
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- last seen: 2026-06-10T17:14:06.276822+00:00
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