Synthesis of high specific activity 17α‐cyanomethyl‐17β‐hydroxy‐[14α,15α‐3H]estra‐4,9‐dien‐3‐one

Peter Droescher, J. Röomer
In: Journal of Labelled Compounds and Radiopharmaceuticals · 1995 · vol. 36(2) , pp. 111–119 · doi:10.1002/jlcr.2580360203 · W2060152899
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Abstract

Abstract An improved synthesis of the tritium labelled form of the new pharmacon DIENOGEST is described. The [ 14 α,15α‐ 3 ‐H]DIENOGEST was obtained with a specific activity of 51 Ci/mmol and a radiochemical purity > 98%.

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