Granular cell tumor of the hypopharynx: a rare case report.

Abstract Introduction: Originating from the Schwann cells; Granular cell tumor is an extremely rare tumor, accounting for 0.5% of all soft tissue tumors. Variant of this tumor can be classified as either as synchronous or metachronous, or either malignant, begin or atypical. We report a scarce case of granular cell tumor of the hypopharynx, adding to the rare count of this entity in this localization, in a 74 years-old female patient. Case presentation : We add to the literature arsenal of this entity by reporting this rare case of benign of granular cell tumor of the hypopharynx in A 74 years-old female patient with hypertension, suffered from dysphonia for about 6 months. Examination identified a budding tumor in the left piriform sinus. Ct scan showcased a 1 cm irregular, spontaneously hypodense, slightly enhanced after injection mass, infiltrating the left piriform sinus. Excisional biopsy confirmed the diagnosis and follow-up was uneventful. Conclusion: This rare neoplasia have variable age, sex and ethnicity predilection; and depending on the localization, nonspecific symptoms and it is usually displays as small, smooth, submucosal lesion. Positive staining for S-100 protein confirms the diagnosis and no harmonized treatment guideline is established.