Haplotypes of endometriosis-related SNPs in HOTAIR and their associations with clinical features.

Cherry Yin-Yi Chang (7224650); Chung-Chen Tseng (10262915); Ming-Tsung Lai (493834); An-Jen Chiang (688755); Lun-Chien Lo (10262918); Chih-Mei Chen (309456); Man-Ju Yen (10262921); Li Sun (4624); Li Yang (6520); Tritium Hwang (10262924); Fuu-Jen Tsai (230856); Jim Jinn-Chyuan Sheu (7326185)

doi:10.1371/journal.pone.0248168.g001

Haplotypes of endometriosis-related SNPs in HOTAIR and their associations with clinical features.

Cherry Yin-Yi Chang (7224650), Chung-Chen Tseng (10262915), Ming-Tsung Lai (493834), An-Jen Chiang (688755), Lun-Chien Lo (10262918), Chih-Mei Chen (309456), Man-Ju Yen (10262921), Li Sun (4624), Li Yang (6520), Tritium Hwang (10262924), Fuu-Jen Tsai (230856), Jim Jinn-Chyuan Sheu (7326185)

2021 · doi:10.1371/journal.pone.0248168.g001 · W6904628887

other OA: green CC0

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Abstract

Two-allele genetic combinations among three endometriosis-related SNPs in HOTAIR, including rs1838169, rs4511324 and rs17720428, were analyzed in patients and correlated with the frequencies of (A) high CA125 levels (> 35.0 U/ml); (B) severe pain (pain score > 5.0); (C) advanced stages (stages 3 and 4); and (D) infertility.

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endometriosisinfertility

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