Clinical evaluation of three methods in the treatment of adenomyosis

In: Clinical and Experimental Obstetrics & Gynecology · 2018 · vol. 45(4) , pp. 508–512 · doi:10.12891/ceog3562.2018 · W3034481218
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AI-generated summary by gemini-2.5-flash-lite, 2026-06-07

This study evaluated hysterectomy, radiofrequency ablation, and GnRH drug treatment for adenomyosis, finding radiofrequency ablation to be a preferred minimally invasive option for women desiring fertility.

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AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text

This retrospective study evaluated three treatment approaches for adenomyosis among 180 patients diagnosed at the First Affiliated Hospital of Xinjiang Medical University between 2010 and 2013: hysterectomy (n=75), ultrasound-guided radiofrequency ablation (n=30), and gonadotropin-releasing hormone (GnRH) conservative drug therapy (n=75). The authors report that hysterectomy was effective but results in loss of reproductive function and potential for premature ovarian failure, while GnRH therapy had limitations including inaccuracy, long treatment course, higher cost, and important side effects. Ultrasound-guided radiofrequency ablation was described as having minimal side effects, shorter hospitalization, lower cost, and preservation of ovarian blood supply and function, particularly aligning with fertility-related goals. A major caveat is that the work is retrospective and includes an unequal group size, which limits the strength of comparative conclusions. This paper is centrally about adenomyosis—specifically clinical evaluation and comparison of hysterectomy, GnRH therapy, and ultrasound-guided radiofrequency ablation for adenomyosis.

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Abstract

Objective: To evaluate the efficacy of three methods in the treatment of adenomyosis (ADM). Materials and Methods: Retrospective analysis of the clinical data of 180 patients with ADM diagnosed in the First Affiliated Hospital of Xinjiang Medical University from2010 January to 2013 January, including 75 cases of hysterectomy (Group A), 30 cases underwent ultrasound guided radiofrequency ablation (group B), and 75 cases of gonadotropin releasing hormone (GnRH) conservative drug treatment (Group C). Results: Hysterectomy is an effective treatment, but the patients will lose reproductive function, and may lead to premature ovarian failure. GnRH drugs are not exact, long course of treatment, the price is expensive, and the side effect is important. radiofrequency ablation has little side effect, hospitalization time is short, less treatment cost, will not change the ovarian blood supply, does not affect ovarian function, for patients with fertility requirements, and uterine aspiration and retention can be used as the preferred method of treatment. Conclusion: Ultrasound guided radiofrequency ablation treatment of uterine adenomyosis, as a minimally invasive technique to preserve the uterus, and radiofrequency ablation is expected to be new targeting ways for ADM, to make up the deficiency of existing treatment methods, maintain the retention period uterine endocrine function and endometrial shedding, maintain the patients physiological and psychological balance, and prevent reproductive tract infection, and is expected to become the safe, effective new way of treatment of ADM.
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Abstract

Objective: To evaluate the efficacy of three methods in the treatment of adenomyosis (ADM). Materials and Methods: Retrospective analysis of the clinical data of 180 patients with ADM diagnosed in the First Affiliated Hospital of Xinjiang Medical University from2010 January to 2013 January, including 75 cases of hysterectomy (Group A), 30 cases underwent ultrasound guided radiofrequency ablation (group B), and 75 cases of gonadotropin releasing hormone (GnRH) conservative drug treatment (Group C). Results: Hysterectomy is an effective treatment, but the patients will lose reproductive function, and may lead to premature ovarian failure. GnRH drugs are not exact, long course of treatment, the price is expensive, and the side effect is important. radiofrequency ablation has little side effect, hospitalization time is short, less treatment cost, will not change the ovarian blood supply, does not affect ovarian function, for patients with fertility requirements, and uterine aspiration and retention can be used as the preferred method of treatment. Conclusion: Ultrasound guided radiofrequency ablation treatment of uterine adenomyosis, as a minimally invasive technique to preserve the uterus, and radiofrequency ablation is expected to be new targeting ways for ADM, to make up the deficiency of existing treatment methods, maintain the retention period uterine endocrine function and endometrial shedding, maintain the patients physiological and psychological balance, and prevent reproductive tract infection, and is expected to become the safe, effective new way of treatment of ADM.

Keywords

- Adenomyosis - Radiofrequency ablation - Surgery - GnRH

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adenomyosis

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