A comparative analysis of clinical characteristics of adenomyosis and hysteromyoma

Objective To investigate differences in clinical characteristics of adenomyosis and hysteromyoma so as to improve preoperative diagnosis rate of adenomyosis.Methods 130 cases of adenomyosis confirmed by pathological examination after hysterectomy in past 5 years and 150 cases of hysteromyoma confirmed by pathological examination after hysterectomy in the same period were randomly selected and their age distribution,past history,clinical symptoms,preoperative diagnosis,ultrasonographic findings and serum level of CA125 were compared.Results Both the diseases were commonly seen in women of childbearing age and the clinical manifestations of the patients were hypermenorrhea or prolonged menstrual period(No difference between the two groups,P0.05).The preoperative diagnosis rate of adenomyosis was 72.31%,and the patients with adenomyosis usually suffered from dysmenorrhea(73.08%),dyspareunia(33.08%) and seldom secondary anemia(15.38%).Ultrasonographic examination showed some characteristic findings and the serum level of CA125(74.5±68.3U/ml) increased evidently.Conclusion Though the golden standard of diagnosis of adenomyosis is pathologic diagnosis,the past history,specific clinical symptoms,ultrasonographic findings,and elevated serum CA125 level are also important reference indexes to differentiate adenomyosis with hysteromyoma before operation.