Progress in Study of Nerve Growth Factor and Its Receptors on Mechanism of Endometriosis Pain

Endometriosis,as a commonlyencountered disease,has a serious effect on women's physical and mental health.The primary symptom is pelvic pain,but the mechanisms of pain are still unclear.Recent studies showed that nerve growth factor(NGF)can promote neural cell proliferation and differentiation,induce the expression and release of neuropeptides and increase the number of sensory neurons through binding nerve cell receptor.It may be play an important role in endometriosis pain and hyperalgesia.NGF and its receptors on mechanism of endometriosis pain will be briefly reviewed in this paper.