子宫内膜异位症及卵巢癌腹腔IL-6、IL-8变化的临床意义
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Abstract
目的：探讨白细胞介素6（IL-6）、白细胞介素8（IL-8）与子宫内膜异位症（endomotriosisEMs）卵巢癌的发生发展关系。方法：采用双抗体夹心ABC-酶联免疫吸附实验（ELISA）对EMs患者30例、血清及腹腔液中IL-6、IL-8进行检测,并以卵巢癌患者10例、卵巢良性肿瘤患者30例、正常妇女血清30例做对照组。结果：EMs组与卵巢癌组患者血清及腹腔液中IL-6、IL-8水平明显高于对照组（P〈0.01）,EMs组与卵巢癌组对比无显著性差异（P〉0.05）。结论：EMs患者腹腔液中IL-6、IL-8异常增高是腹腔免疫内环境失衡,与EMs的发生发展有关,在药物治疗中血清IL-6、IL-8可作为EMs疗效和预后的指标之一。
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- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
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