Immediate Redo Hepatic Artery Reconstruction in Living Donor Liver Transplantation

Immediate Redo Hepatic Artery Reconstruction in Living Donor Liver Transplantation | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Immediate Redo Hepatic Artery Reconstruction in Living Donor Liver Transplantation Muhammad Zafar This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-5633410/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background: In living donor liver transplant, vascular complications by compromising the blood flow to the graft can have significant and sometimes might lead to life-threatening consequences for the patient. Aim: To evaluate the practice of immediate redo hepatic artery reconstruction in living donor liver transplant. Methods: Across sectional study (June 2003-August 2015) included recipients with hepatic artery complication who underwent living donor liver transplantation at Chang Gung Memorial Hospital, Kaohsiung, Taiwan. Intraoperative complications necessitating immediate redo reconstruction of hepatic arterywere recorded. Vascular patency was evaluated by intraoperative and postoperative Doppler Ultrasonography. Immediate redo reconstruction was carried out when either arterial wall problem or low flow or RI less than 0.55. Late redo reconstruction (> 24 hours) was carried out to patients developed HAT postoperatively. The data was analyzed by SPSS version 21. P value less than 0.05 was regarded as significant. Results: A59 recipients developed hepatic artery complication,and underwent redo reconstruction with incidence of 6.6%. Immediate redo reconstruction was performed in 86.4%, and 13.6% underwent late redo reconstruction (>24 hours). Minimal discrepancy was encountered in 71.2%, and there was significant correlation between discrepancy and RI, (p=0.048). RI <0.55 was seen in 25.4%. There was significant difference in the outcome between the groups of patient managed by early versus late HA redo reconstruction, (p=0.031). Conclusion: Preliminary results show that immediate redo HA reconstruction preserving blood flow, maintaining perfusion and preventing post-transplant graft loss. Hepatobiliary & Transplant Surgery Hepatic artery (HA) complications reconstruction redo reconstruction resistive index Full Text Additional Declarations The authors declare no competing interests. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-5633410","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":389639921,"identity":"f9b260f0-48f8-474f-b769-dffe134e5ee7","order_by":0,"name":"Muhammad Zafar","email":"data:image/png;base64,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","orcid":"https://orcid.org/0009-0008-6179-7400","institution":"Department of Surgery, Chang Gung University College of Medicine, Taiwan Submission: October 08, 2016; Published: October 22, 2016 *Corresponding author: Muhammad Zafar Mengal, Liver Transpl Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan.","correspondingAuthor":true,"prefix":"","firstName":"Muhammad","middleName":"","lastName":"Zafar","suffix":""}],"badges":[],"createdAt":"2024-12-12 17:23:15","currentVersionCode":1,"declarations":{"humanSubjects":true,"vertebrateSubjects":false,"conflictsOfInterestStatement":false,"humanSubjectEthicalGuidelines":true,"humanSubjectConsent":true,"humanSubjectClinicalTrial":true,"humanSubjectCaseReport":false,"vertebrateSubjectEthicalGuidelines":false},"doi":"10.21203/rs.3.rs-5633410/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-5633410/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":71473173,"identity":"e4b33c99-8772-4935-85cb-e94aa432b227","added_by":"auto","created_at":"2024-12-16 04:36:47","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":188723,"visible":true,"origin":"","legend":"","description":"","filename":"1286ImmediateRedoHepaticArteryReconstructioninLivingDonorLiverTransplantation.pdf","url":"https://assets-eu.researchsquare.com/files/rs-5633410/v1_covered_2ed2bc83-e898-49c9-a7b5-f6ae342b4988.pdf"}],"financialInterests":"The authors declare no competing interests.","formattedTitle":"\u003cp\u003eImmediate Redo Hepatic Artery Reconstruction in Living Donor Liver Transplantation\u003c/p\u003e","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":true,"highlight":"","institution":"kcgmh taiwan","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Hepatic artery (HA), complications, reconstruction, redo reconstruction, resistive index","lastPublishedDoi":"10.21203/rs.3.rs-5633410/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-5633410/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground: \u003c/strong\u003eIn living donor liver transplant, vascular complications by compromising the blood flow to the graft can have significant and sometimes might lead to life-threatening consequences for the patient.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAim:\u003c/strong\u003e To evaluate the practice of immediate redo hepatic artery reconstruction in living donor liver transplant.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethods:\u003c/strong\u003e Across sectional study (June 2003-August 2015) included recipients with hepatic artery complication who underwent living donor liver transplantation at Chang Gung Memorial Hospital, Kaohsiung, Taiwan. Intraoperative complications necessitating immediate redo reconstruction of hepatic arterywere recorded. Vascular patency was evaluated by intraoperative and postoperative Doppler Ultrasonography. Immediate redo reconstruction was carried out when either arterial wall problem or low flow or RI less than 0.55. Late redo reconstruction (\u0026gt; 24 hours) was carried out to patients developed HAT postoperatively. The data was analyzed by SPSS version 21. P value less than 0.05 was regarded as significant.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults:\u003c/strong\u003e A59 recipients developed hepatic artery complication,and underwent redo reconstruction with incidence of 6.6%. Immediate redo reconstruction was performed in 86.4%, and 13.6% underwent late redo reconstruction (\u0026gt;24 hours). Minimal discrepancy was encountered in 71.2%, and there was significant correlation between discrepancy and RI, (p=0.048). RI \u0026lt;0.55 was seen in 25.4%. There was significant difference in the outcome between the groups of patient managed by early versus late HA redo reconstruction, (p=0.031).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusion:\u003c/strong\u003e Preliminary results show that immediate redo HA reconstruction preserving blood flow, maintaining perfusion and preventing post-transplant graft loss.\u003c/p\u003e","manuscriptTitle":"Immediate Redo Hepatic Artery Reconstruction in Living Donor Liver Transplantation","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2024-12-16 04:28:40","doi":"10.21203/rs.3.rs-5633410/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"63884010-a756-4b92-b9da-c5d556bd41f0","owner":[],"postedDate":"December 16th, 2024","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[{"id":41530470,"name":"Hepatobiliary \u0026 Transplant Surgery"}],"tags":[],"updatedAt":"2024-12-16T04:28:40+00:00","versionOfRecord":[],"versionCreatedAt":"2024-12-16 04:28:40","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-5633410","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-5633410","identity":"rs-5633410","version":["v1"]},"buildId":"qtupq5eGEP_6zYnWcrvyt","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}