EP31.01: Is the World Endometriosis Research Foundation (WERF) Endometriosis Phenome and Biobanking Harmonisation Project (EPHect) questionnaire a good triaging tool for women with ovarian and posterior compartment endometriosis?

We aim to demonstrate whether the WERF EPHect questionnaire can be used as a triaging tool to determine which women, based upon symptoms, are more likely to have ovarian and posterior compartment endometriosis on ultrasound. Prospective observational study (July 2018 to March 2019). Women referred for a ‘deep endometriosis’ (DE) ultrasound to two specialised centres with a history of possible endometriosis, were emailed the online WERF EPHect questionnaire. The DE ultrasounds were performed by advanced sonologists as per the IDEA consensus opinion. A subsection of the questionnaire focusing on bowel symptoms (during menses and in the preceding 3 months) was compared to DE ultrasound findings. Logistic regression analysis was performed to assess the correlation between online responses and ultrasound findings. 217 women were emailed the online questionnaire; 136/217 (62%) responded prior to their DE ultrasound. The ultrasound prevalence of ovarian endometriomas, rectal DE and complete pouch of Douglas (POD) obliteration on ultrasound were 24%, 18% and 18%, respectively. There was no significant difference in the prevalence of disease in the respondents versus non-respondents (47%/47% posterior compartment, 31%/24% ovarian, respectively (p-value<0.05)). Older age, blood and mucus in stool and fullness and bloating were significant predictors of ovarian disease. Older age and blood in stool were predictive of posterior compartment disease, specifically rectal DE and POD obliteration. When the WERF EPHect questionnaire is applied, bowel symptoms have the potential to be utilised as a triaging tool to determine which women require DE ultrasounds. A structured international symptomatology survey may be able to better target the utility of the DE ultrasound. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.