VEGF、Ang-2、Tie-2在子宫内膜异位症不同临床分期中的表达及意义
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Abstract
子宫内膜异位症（Endometriosis,EMs）是指子宫内膜组织出现在子宫体以外部位时所引发的一种疾病,是常见的妇科疾病,异位内膜以侵犯卵巢为多见,称卵巢巧克力囊肿。其在育龄妇女中的发病率为5%-15%,在不孕妇女中发病率高达40%-50%。本病发病机制尚未完全阐明,随着分子生物学的发展和血管生成理论的进一步研究,越来越多的证据表明血管生成是EMs发生、发展的重要环节,子宫内膜血管生成紊乱可能是EMs发病的基础。血管发生过程受体内多种促进血管生长因子的调控,最常见的有VEGF和血管生成素（Angiopoietin,Ang）家族。
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- last seen: 2026-06-10T17:14:06.276822+00:00
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