Clinical values of four markers in diagnosis of pelvic mass

Aim To study the clinical value of CA_ 125 ,CA_ 199 ,CEA and AFP in diagnosis of female pelvic mass.Method During one week before operation,the serum from 208 patients suffering from pelvic masses were assayed for CA_ 125 ,CA_ 199 ,CEA by Micropartical enzyme immunoassay(MEIA) and for AFP by radio immunoassay(RIA).Results (1)CA_ 125 and CA_ 199 were higher in malignant mass than in benign mass,particularly CA_ 125 .The CA_ 125 positive rates in maligant mass and benign mass were 36.3%,76.0% respectively,but CEA,AFP positive rates were low.(2) The CA_ 125 positive rates in endometrioma and endometriosis were 74.36%,58.14% respectively and were higher than else benign masses.So the CA_ 125 had differential diagnosis value.Conclusion The CA_ 125 is an appropriate marker in diffrentiating pelvic masses.Clinical value of CEA is limited.