Impact of Laparoscopic Ovarian Cystectomy on Serum Follicle Stimulating Hormone: A study among Women with Unilateral Endometrioma

Objective: To evaluae the difference in the serum follicle stimulating hormone (FSH) before and after laparoscopic ovarian cystectomy among women with unilateral endometrioma.  Methods: A quasi-experimental study was conducted at the Patel Hospital, Karachi from April to December 2017. All women of reproductive age (20-40 years) having ultrasonographic indings of 2 unilateral endometrioma of more than 4 cm and body mass index <30kg/m were enrolled. All women were subjected to laproscopical removal of ovarian cyst. The serum FSH were measured preoperatively and 3 months postoperatively. Mean change in ovarian FSH level was noted. The mean difference in FSH level pre and post laproscopic cystectomy were taken as mean change. Results: Of 83 women with unilateral endometrioma, mean age of the women was 24.51±2.85 years. 2 There were 59 (71%) women with normal weight (BMI 18-25 kg/m ) whereas multiparity was observed in 42 (51%) women. A significant increase in the serum FSH was observed post operatively, i.e. the mean serum FSH pre-operatively was 5.69±1.15 mIU/mL while serum FSH post-operatively was 7.68±1.55 mIU/mL. The mean change of 1.99 mIU/mL was noted (p-value <0.001). A signiicant increase in serum FSH level was observed when stratiied on the basis of age (p-value <0.001), BMI (p-value <0.001), cyst size (p-value <0.001), duration of symptoms (p-value <0.001), marital status (p-value <0.001), occupation (pvalue <0.001), education (p-value <0.001), and parity (p-value <0.001).  Conclusion: A considerable upsurge in the serum FSH level was noted after laparoscopic cystectomy among women with unilateral endometrioma.