RGD cycle peptide inhibits development of experimental endometriosis.

Experimental endometriosis was induced in wild-type mice with wild-type endometrial fragments which were pre-treated with either vehicle (Veh) or RGD peptide (RGD) and development of ectopic lesions was assessed as described under “Materials and Methods.” Data are displayed as the mean ± SEM. Different letters indicate statistically significant differences among the means between treatments as determined by unpaired t-tests (N = 8/group). B Chi square analysis of the proportion of mice which received implant tissue pre-treated with either vehicle (Veh) or RGD cyclic peptide (RGD).