Association between IL33-rs146597587 and asthma, allergic rhinitis, or endometriosis risk in the UK Biobank.

Abdou Mousas (4336705), Georgios Ntritsos (4336708), Ming-Huei Chen (73691), Ci Song (396329), Jennifer E. Huffman (220403), Ioanna Tzoulaki (257920), Paul Elliott (27295), Bruce M. Psaty (103721), Paul L. Auer (3987392), Andrew D. Johnson (150072), Evangelos Evangelou (64006), Guillaume Lettre (163230), Alexander P. Reiner (178706)
2017 · doi:10.1371/journal.pgen.1006925.t003 · W6904378094
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Abstract

All analyses were corrected for age, sex, and the first 10 principal components. The direction of the odds ratio is for the rare allele (rs146597587, C-allele on forward strand). The conditional P-values were calculated in a logistic model accounting for genotypes at common single nucleotide polymorphisms (SNPs) previously associated with asthma, allergic rhinitis, or endometriosis: rs343496, rs7032572, rs72699186, rs1342326, rs2381416, rs928413, rs10975519.
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Rare coding variants pinpoint genes that control human hematological traits Table 3 Association between IL33-rs146597587 and asthma, allergic rhinitis, or endometriosis risk in the UK Biobank. All analyses were corrected for age, sex, and the first 10 principal components. The direction of the odds ratio is for the rare allele (rs146597587, C-allele on forward strand). The conditional P-values were calculated in a logistic model accounting for genotypes at common single nucleotide polymorphisms (SNPs) previously associated with asthma, allergic rhinitis, or endometriosis: rs343496, rs7032572, rs72699186, rs1342326, rs2381416, rs928413, rs10975519.

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