Perceived social support and depressive symptoms in Chinese patients with ovarian cancer and the mediating role of resilience

Perceived social support and depressive symptoms in Chinese patients with ovarian cancer and the mediating role of resilience | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research article Perceived social support and depressive symptoms in Chinese patients with ovarian cancer and the mediating role of resilience Xiaoyan Pang, Haiyan Dong, Lei Deng, Yi Zhang This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-228614/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background Patients with ovarian cancer (OC) often suffer from depressive symptoms, but there is little research on coping style such as perceived social support and resilience. The aim of the present study was to explore whether resilience plays a mediating role between perceived social support and depressive symptoms. Methods A cross-sectional study was performed between August 2018 and March 2019. Perceived social support, resilience, and depressive symptoms were measured with the Multi‐dimensional Scale of Perceived Social Support (MSPSS), the Center for Epidemiologic Studies-Depression (CES-D) scale and the Connor‐Davidson Resilience Scale (CD‐RISC). Hierarchical linear regression analyses were used to assess the mediating role of resilience between these variables. Results Of 230 consecutive patients identified, a total of 217 completed questionnaires. After controlling for covariates, perceived social support was negatively correlated with depressive symptoms (β = -0.482, p < 0.01) and explained 22.8% of the variance. In addition, after controlling for covariates and perceived social support, resilience was also negatively associated with depressive symptoms (β = -0.492, p < 0.01) and explained 18.1% of the variance. Bootstrapping test confirmed that the BCa 95% CI for resilience excludes 0 in Table 4 (BCa95% CI: -0.342, -0.143), therefore resilience partially mediated the associations of perceived social support with depressive symptoms. Conclusions Results revealed that resilience could mediate the association between social support and depressive symptoms, and concluded that it was critical to focus on social support as well as resilience in the management strategy of OC. Psychiatry ovarian cancer depression resilience perceived social support Full Text Due to technical limitations, full-text HTML conversion of this manuscript could not be completed. However, the manuscript can be downloaded and accessed as a PDF. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-228614","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Research article","associatedPublications":[],"authors":[{"id":11236470,"identity":"1a926188-74dd-4d4e-ae1b-3a6cd41ee11c","order_by":0,"name":"Xiaoyan Pang","email":"","orcid":"","institution":"The First Affiliated Hospital of China Medical University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Xiaoyan","middleName":"","lastName":"Pang","suffix":""},{"id":11236471,"identity":"4c06058f-3b9b-4c97-88e6-b0469f80b917","order_by":1,"name":"Haiyan Dong","email":"","orcid":"","institution":"The First Affiliated Hospital of China Medical University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Haiyan","middleName":"","lastName":"Dong","suffix":""},{"id":11236472,"identity":"6da38f3c-b6e6-43f7-8475-f154d0bdbd42","order_by":2,"name":"Lei Deng","email":"","orcid":"","institution":"The First Affiliated Hospital of China Medical University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Lei","middleName":"","lastName":"Deng","suffix":""},{"id":11236473,"identity":"4ec49787-b2cd-40ab-a8f8-f1b0906b77ae","order_by":3,"name":"Yi Zhang","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAAn0lEQVRIiWNgGAWjYJCCAx8MbOxI03JwRkFaMmlamHk+HGJsIFq5/Iz0h4dtDA4wM7AfPrqBKC0GNxISDucY3OFj4ElLu0GcFomEA0Atz5gZJHjMiNMiPyOx4bCFwWHGBqK1MNxIZjjMQJIWgzPPGA72GKQlsxHtF/n29McffvyxseNnP3yMSIcJJEBoNuKUgwD/AeLVjoJRMApGwQgFAM5vMMea+P94AAAAAElFTkSuQmCC","orcid":"https://orcid.org/0000-0003-1150-6042","institution":"First Affiliated Hospital of China Medical University","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"Yi","middleName":"","lastName":"Zhang","suffix":""}],"badges":[],"createdAt":"2021-02-10 13:01:13","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-228614/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-228614/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":13660736,"identity":"58fcb236-fb5f-4885-9cbc-16d6ffb41f7f","added_by":"auto","created_at":"2021-09-17 10:26:11","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":117643,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-228614/v1/2ace2612-6bbd-4441-8a8b-aa329b86ceaf.pdf"}],"financialInterests":"","formattedTitle":"Perceived social support and depressive symptoms in Chinese patients with ovarian cancer and the mediating role of resilience","fulltext":[{"header":"Full Text","content":"\u003cp\u003eDue to technical limitations, full-text HTML conversion of this manuscript could not be completed. 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The aim of the present study was to explore whether resilience plays a mediating role between perceived social support and depressive symptoms. \u003c/p\u003e\u003cp\u003eMethods\u003c/p\u003e\u003cp\u003eA cross-sectional study was performed between August 2018 and March 2019. Perceived social support, resilience, and depressive symptoms were measured with the Multi‐dimensional Scale of Perceived Social Support (MSPSS), the Center for Epidemiologic Studies-Depression (CES-D) scale and the Connor‐Davidson Resilience Scale (CD‐RISC). Hierarchical linear regression analyses were used to assess the mediating role of resilience between these variables. \u003c/p\u003e\u003cp\u003eResults\u003c/p\u003e\u003cp\u003eOf 230 consecutive patients identified, a total of 217 completed questionnaires. After controlling for covariates, perceived social support was negatively correlated with depressive symptoms (β = -0.482, p \u0026lt; 0.01) and explained 22.8% of the variance. 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