Pregnancy and SARS-CoV-2: an opportunity to systematically study the complexity of maternal health

Barr E, Elizabeth Barr, Damiya Whitaker, Whitaker D, Pamela Stratton, Stratton P
The Lancet. Digital health · 2022 · vol. 4(2) , pp. e76–e77 · doi:10.1016/s2589-7500(21)00277-6 · PMID:35034864 · PMC8758151
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This paper, acknowledging potential conflicts of interest from authors regarding maternal health and pain management, presents an opportunity to systematically study the complexity of maternal health, particularly in the context of pregnancy and SARS-CoV-2.

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This brief editorial commentary highlights pregnancy as a unique biological window to investigate the intricate mechanisms underlying maternal health disorders. The authors, including experts with significant ties to endometriosis research and treatment advisory panels, argue that studying physiological changes during gestation can provide critical insights into conditions like chronic pelvic pain and endometriosis. They emphasize the potential for systematic data collection during this period to unravel complex pathophysiological pathways that are difficult to study outside of pregnancy. Relevance to endometriosis: listed as one indication for GnRH antagonists, though the paper's main focus is uterine fibroids.

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Coi Statement

EB and DW declare no competing interests. PS declares royalties and fees paid by UpToDate for a chapter on Diagnosis and Management of Acute Pelvic Pain; McGraw Hill for a chapter in Current Diagnosis and Treatment—Obstetrics and Gynecology; Current Obstetrics and Gynecology Reports for work as a Section Editor on Endometriosis; AbbVie for being a member of the advisory panel on treatment of chronic pelvic pain with botulinum toxin; World Endometriosis Research Foundation for being a member of a panel developing pain specific physical examination criteria; and American Society for Reproductive Medicine for an award for the best clinical abstract in Endometriosis. The acknowledgments are available in the appendix .

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MeSH descriptors

COVID-19 SARS-CoV-2 Female Humans Maternal Health Pregnancy Pregnancy Outcome

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License: CC-BY-NC-ND-4.0