Binaural Advantage Enhances the Mismatch Negativity and Interhemispheric Connectivity During Gap Detection

Binaural Advantage Enhances the Mismatch Negativity and Interhemispheric Connectivity During Gap Detection | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 29 September 2025 V1 Latest version Share on Binaural Advantage Enhances the Mismatch Negativity and Interhemispheric Connectivity During Gap Detection Authors : Thomas Augereau 0000-0001-6175-674X [email protected] , François Champoux , and Victoria Duda 0000-0002-2593-7655 Authors Info & Affiliations https://doi.org/10.22541/au.175918876.60661427/v1 181 views 114 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract not-yet-known not-yet-known not-yet-known unknown Binaural hearing provides a perceptual advantage in detecting brief gaps in sound, yet the neural mechanisms underlying this benefit remain poorly understood. This study examined the cortical dynamics and lateralization associated with the binaural advantage and ear advantage in auditory gap detection using event-related potentials (ERPs) and effective connectivity analysis. Sixteen normal-hearing adults were presented with monaural (left and right ear) and binaural broadband pink noise stimuli containing silent gaps of varying durations, while EEG was recorded. We analyzed the Mismatch Negativity (MMN) to assess auditory gap detection. Source-localized activity and Granger causality were analyzed across ten functionally defined scouts to evaluate cortical dynamics and effective connectivity underlying ear asymmetry and binaural advantage. Results revealed significantly larger and earlier MMN responses in the binaural condition compared to monaural presentations, with stronger activation in contralateral temporal clusters for monaural conditions. Source-localized activity and effective connectivity exploratory analyses showed an overall enhanced activation for binaural stimulation for the standard stimuli. However, despite the stronger MMN observed in the binaural difference wave, source activity revealed a pattern of binaural suppression. Connectivity analyses further showed pronounced variations originating from the left auditory cortex and temporal gyri depending on listening condition, whereas connectivity involving the right auditory cortex varied as a function of gap duration. Together, these findings suggest that the binaural advantage relies on more efficient, facilitated mechanisms, while monaural stimulation requires increased cortical activity and connectivity to support temporal discrimination. Supplementary Material File (manuscript.pdf) Download 3.76 MB Information & Authors Information Version history V1 Version 1 29 September 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords auditory temporal resolution binaural advantage effective connectivity hemispheric asymmetry mismatch negativity Authors Affiliations Thomas Augereau 0000-0001-6175-674X [email protected] Université de Montréal View all articles by this author François Champoux Université de Montréal View all articles by this author Victoria Duda 0000-0002-2593-7655 Université de Montréal View all articles by this author Metrics & Citations Metrics Article Usage 181 views 114 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Thomas Augereau, François Champoux, Victoria Duda. Binaural Advantage Enhances the Mismatch Negativity and Interhemispheric Connectivity During Gap Detection. Authorea . 29 September 2025. DOI: https://doi.org/10.22541/au.175918876.60661427/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. 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