Expression and significance of VEGF in endometriosis

In: Yixue yanjiusheng xuebao · 2003 · W2367034261
article OA: closed CC0
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Abstract

Objectvies:To investigate the role of vascular endothelial growth factor(VEGF) in the pathogenesis of endometriosis(EMs). Methods:A total of 70 specimens of endometriosis and 30 specimens of the normal controls were evaluated by immunohistologically techique with polyclonal antibody against VEGF. Results:The expression levels of VEGF in endometriotic tissues was higher than that in the normal endometrium( P 0.001). Conclusions:VEGF was overexpressed in endometriotic tissues.There was closed relationships between VEGF and endometriosis angiogenesis.VEGF played an important role in the progression of endometriosis.

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endometriosis

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