Off-Pump CABG in Interstitial Lung Disease: Navigating the Perfect Storm of Pulmonary and Cardiac Comorbidities

Off-Pump CABG in Interstitial Lung Disease: Navigating the Perfect Storm of Pulmonary and Cardiac Comorbidities | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Case Report Off-Pump CABG in Interstitial Lung Disease: Navigating the Perfect Storm of Pulmonary and Cardiac Comorbidities Dr. NISHAT TAMANNA RUPA, Dr. Apu Das This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-9637895/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background: Cardiovascular surgery patients with interstitial lung disease (ILD) have a significantly higher risk of complications during the operation as a result of impaired lung function and increased inflammatory reactions. Case Summary: A 61-year-old man had off-pump CABG using great saphenous vein conduits from both legs due to idiopathic pulmonary fibrosis-pattern ILD and triple-vessel coronary artery disease (TVD). Significant epistaxis while on dual antiplatelet treatment, hypoalbuminemia, a protracted respiratory recovery, and sternal dehiscence necessitating rewiring within 9 days after CABG all added complications to his postoperative course. Final healing and release from the hospital occurred on the 24th postoperative day as a result of thorough interdisciplinary care. While coronary artery bypass grafting (CABG) can help ILD patients avoid lung damage from cardiopulmonary bypass, it comes with its own set of postoperative and technical issues, such as the possibility of bleeding, wound healing complications, and graft patency. Off-pump coronary artery bypass grafting (CABG) Interstitial lung disease (ILD) Idiopathic pulmonary fibrosis (IPF) Triple-vessel coronary artery disease (TVD) Nintedanib Sternal dehiscence Postoperative complications Figures Figure 1 Full Text Additional Declarations The authors declare no competing interests. Participant Consent to Publish: Written informed consent was obtained from the patient for participation in this study and for the publication of this clinical case report, including any accompanying clinical details and images. Supplementary Files Consent.pdf Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-9637895","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Case Report","associatedPublications":[],"authors":[{"id":635939812,"identity":"dfd41c9b-21fc-48e0-a27b-ad8fce9f8a84","order_by":0,"name":"Dr. NISHAT TAMANNA 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