Letter to the Editor “Left Atrial Appendage Thrombus Under Anticoagulation in Atrial Fibrillation…. The Management Is Still Being Debated” by Antoine Da Costa et al. based on Alexander Kushnir et al. “Persistent Left Atrial Appendage Thrombus in Atrial Fibrillation Despite Anticoagulation. J Cardiovasc Electrophysiol 2025 May 15. doi: 10.1111/jce.16718. Online ahead of print.”

Letter to the Editor “Left Atrial Appendage Thrombus Under Anticoagulation in Atrial Fibrillation…. The Management Is Still Being Debated” by Antoine Da Costa et al. based on Alexander Kushnir et al. “Persistent Left Atrial Appendage Thrombus in Atrial Fibrillation Despite Anticoagulation. J Cardiovasc Electrophysiol 2025 May 15. doi: 10.1111/jce.16718. Online ahead of print.” | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL Journal of Cardiovascular Electrophysiology This is a preprint and has not been peer reviewed. Data may be preliminary. 20 June 2025 V1 Latest version Share on Letter to the Editor “Left Atrial Appendage Thrombus Under Anticoagulation in Atrial Fibrillation…. The Management Is Still Being Debated” by Antoine Da Costa et al. based on Alexander Kushnir et al. “Persistent Left Atrial Appendage Thrombus in Atrial Fibrillation Despite Anticoagulation. J Cardiovasc Electrophysiol 2025 May 15. doi: 10.1111/jce.16718. Online ahead of print.” Authors : Antoine Da Costa 0000-0003-3302-9988 [email protected] , Romain Pierrard , Cedric Yvorel , and Karim Benali Authors Info & Affiliations https://doi.org/10.22541/au.175039402.21232724/v1 263 views 191 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract The management of left atrial appendage thrombus under anticoagulants is still on debate. The paper presented by Kushnir et al. is based on their real-life experience (1). They proposed to switch oral anticoagulation (OAC) or to maintain the same agent for longer period of time allowing to resolve the thrombus in 31% of cases. They also suggest new alternatives such as LAA-occlusion (LAA-O). From our point of view many other strategies remain possible including NOACs substituted by VKA antagonists along with INR values between 3 and 4, LMWH curative therapy or the rivaroxaban 15 mg twice daily dose use for a period of 8 weeks before TEE retesting. Once the clot is dissolved, the TTP-LACC procedure should be discussed or applied in order to avoid the risk LAA thrombus recurrence. This should be the best approach in the future. Supplementary Material File (la thrombus jce letter response 18.06.2025 (1).docx) Download 33.60 KB Information & Authors Information Version history V1 Version 1 20 June 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Collection Journal of Cardiovascular Electrophysiology Keywords clinical: cardiac anatomy clinical: catheter ablation – atrial fibrillation clinical: non-invasive techniques – echo Authors Affiliations Antoine Da Costa 0000-0003-3302-9988 [email protected] Universite Jean Monnet Saint-Etienne View all articles by this author Romain Pierrard Universite Jean Monnet Saint-Etienne View all articles by this author Cedric Yvorel Universite Jean Monnet Saint-Etienne View all articles by this author Karim Benali Universite Jean Monnet Saint-Etienne View all articles by this author Metrics & Citations Metrics Article Usage 263 views 191 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Antoine Da Costa, Romain Pierrard, Cedric Yvorel, et al. Letter to the Editor “Left Atrial Appendage Thrombus Under Anticoagulation in Atrial Fibrillation…. The Management Is Still Being Debated” by Antoine Da Costa et al. based on Alexander Kushnir et al. “Persistent Left Atrial Appendage Thrombus in Atrial Fibrillation Despite Anticoagulation. J Cardiovasc Electrophysiol 2025 May 15. doi: 10.1111/jce.16718. Online ahead of print.”. Authorea . 20 June 2025. DOI: https://doi.org/10.22541/au.175039402.21232724/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . 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