CA-125-Werte bei entzündlicher Adnexerkrankung und Endometriose

Sonsalla R, R. Sonsalla, E Kuss, Kuss E, E. Kuß, J. Zander, Zander J
Geburtshilfe und Frauenheilkunde · 1987 · vol. 47(07) , pp. 499–500 · doi:10.1055/s-2008-1035861 · PMID:3305148 · W2395712828
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-16 ⓘ

Elevated CA-125 levels were observed in a patient with inflammatory adnexitis and a patient with endometriosis, with levels fluctuating post-operatively in the latter.

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The paper reports serial measurements of the tumor marker CA-125 in two clinical cases: a 22-year-old during inflammatory adnexitis, where CA-125 was 478 kU/l and fell to 70 kU/l after inflammation subsided following laparoscopic assessment that largely excluded malignancy. In a second case, a 34-year-old with known endometriosis (10-year history) and acute suppurative fibrinous peritonitis had a CA-125 level of 205 kU/l, with postoperative values of about 165 kU/l on day 4, 273 kU/l on day 13, and 168 kU/l on day 26 despite no signs of inflammation. The main limitation is that these are single-patient case observations rather than a systematic study. This paper is centrally about endometriosis — it includes a case with long-standing endometriosis and reports the associated CA-125 levels during acute peritonitis and postoperative follow-up.

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Abstract

The serum concentration of the tumour marker CA 125 was determined during an inflammatory adnexitis of a young woman of 22 years of age, the measured value being 478 kU/l. After the inflammation had subsided, a malignoma was largely excluded by laparoscopy; the CA 125 value had dropped to 70 kU/l. In a woman of 34 years of age who had an endometriosis that had been identified for the last ten years, as well as an acute suppurative fibrinous peritonitis, the CA 125 value was found to be 205 kU/l. On the fourth postoperative day the value was around 165 kU/l, on the 13th and 26th postoperative day 273 kU/l and 168 kU/l, respectively. There were no signs of an inflammation.
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Subscribe to RSS DOI: 10.1055/s-2008-1035861 © Georg Thieme Verlag Stuttgart · New York CA-125-Werte bei entzündlicher Adnexerkrankung und Endometriose CA 125 Values in Inflammatory Adnexitis and EndometriosisPublication History Publication Date: 19 March 2008 (online) Zusammenfassung Während der entzündlichen Adnexerkrankung einer 22jährigen Patientin wurde die Serumkonzentration des Tumormarkers CA-125 bestimmt und der Wert 478 kU/l gemessen. Nach Abklingen der Entzündung wurde ein Malignom durch Laparoskopie weitestgehend ausgeschlossen, der CA-125-Wert war auf 70 kU/l abgefallen. Bei einer 34jährigen Patientin mit einer seit 10 Jahren bekannten Endometriose und einer akut aufgetretenen eitrig-fibrinösen Peritonitis wurde der CA-125-Wert mit 205 kU/l bestimmt. Am 4. postoperativen Tag lag der Wert bei 165 kU/l, am 13. und 26. postoperativen Tag wurden die Werte 273 kU/l und 168 kU/l gemessen. Entzündungszeichen lagen nicht vor. Abstract The serum concentration of the tumour marker CA 125 was determined during an inflammatory adnexitis of a young woman of 22 years of age, the measured value being 478 kU/l. After the inflammation had subsided, a malignoma was largely excluded by laparoscopy; the CA 125 value had dropped to 70 kU/l. In a woman of 34 years of age who had an endometriosis that had been identified for the last ten years, as well as an acute suppurative fibrinous Peritonitis, the CA 125 value was found to be 205 kU/l. On the fourth postoperative day the value was around 165 kU/l, on the 13th and 26th postoperative day 273 kU/l and 168 kU/l, respectively. There were no signs of an inflammation.

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Condition tags

endometriosis

MeSH descriptors

Antigens, Neoplasm Endometriosis Genital Neoplasms, Female Pelvic Inflammatory Disease Adult Antigens, Neoplasm Antigens, Tumor-Associated, Carbohydrate Diagnosis, Differential Endometriosis Female Genital Neoplasms, Female Humans Ovarian Cysts Ovarian Cysts Ovarian Neoplasms Ovarian Neoplasms Pelvic Inflammatory Disease Ultrasonography

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