WITHDRAWN: Effectiveness of Intraoperative Dexmedetomidine on Early Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Video-Assisted Thoracoscopic Lobectomy: A Randomized Controlled Trial

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This randomized controlled trial investigated the effectiveness of intraoperative dexmedetomidine in preventing early postoperative cognitive dysfunction in elderly patients undergoing video-assisted thoracoscopic lobectomy.

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This withdrawn Research Square preprint was described as a randomized controlled trial testing whether intraoperative dexmedetomidine affects early postoperative cognitive dysfunction in elderly patients undergoing video-assisted thoracoscopic lobectomy. However, the only available full-text content states that the preprint was withdrawn due to concerns about alignment with another related Shi et al. (2020) study that cited the same trial registration but reportedly had divergent research protocols and outcomes. As a result, the paper should not be cited until discrepancies are clarified in a revised publication, and the withdrawn status limits any interpretability of its findings. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Abstract 23, February, 2024. Research Square has withdrawn this preprint as concerns have been raised (https://pubpeer.com/publications/8DFB6F002B66C99339E8A9696B3310) about the alignment between this study and another by Shi et al. (2020) "Dexmedetomidine improves early postoperative neurocognitive disorder in elderly male patients undergoing thoracoscopic lobectomy". Experimental and Therapeutic Medicine, 20, 3868-3877 (https://doi.org/10.3892/etm.2020.9113). Despite both studies citing the same clinical trial registration, they detail divergent research protocols and outcomes. Due to these significant discrepancies with the information registered for the trial, we have opted to withdraw the paper, and this preprint should not be cited as these important issues need to be clarified in a revised publication.
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WITHDRAWN: Effectiveness of Intraoperative Dexmedetomidine on Early Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Video-Assisted Thoracoscopic Lobectomy: A Randomized Controlled Trial | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article WITHDRAWN: Effectiveness of Intraoperative Dexmedetomidine on Early Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Video-Assisted Thoracoscopic Lobectomy: A Randomized Controlled Trial Na He, Haixia Shi, Yajuan Hu, Alberto Uribe, Xinhua Mu, Fei Song, and 1 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-127973/v2 This work is licensed under a CC BY 4.0 License Status: Posted Version 2 posted You are reading this latest preprint version Show more versions Editorial Note 23, February, 2024. Research Square has withdrawn this preprint as concerns have been raised about the alignment between this study and another by Shi et al. (2020) "Dexmedetomidine improves early postoperative neurocognitive disorder in elderly male patients undergoing thoracoscopic lobectomy". Experimental and Therapeutic Medicine, 20, 3868-3877 . Despite both studies citing the same clinical trial registration, they detail divergent research protocols and outcomes. Due to these significant discrepancies with the information registered for the trial, we have opted to withdraw the paper, and this preprint should not be cited as these important issues need to be clarified in a revised publication. Editorial notes are used to provide important context regarding the topic of a preprint or to alert readers to potential issues concerning that preprint or a downstream publication associated with it. For more information on editorial notes, see our Editorial Policies . Abstract 23, February, 2024. Research Square has withdrawn this preprint as concerns have been raised (https://pubpeer.com/publications/8DFB6F002B66C99339E8A9696B3310) about the alignment between this study and another by Shi et al. (2020) "Dexmedetomidine improves early postoperative neurocognitive disorder in elderly male patients undergoing thoracoscopic lobectomy". Experimental and Therapeutic Medicine, 20, 3868-3877 (https://doi.org/10.3892/etm.2020.9113). Despite both studies citing the same clinical trial registration, they detail divergent research protocols and outcomes. Due to these significant discrepancies with the information registered for the trial, we have opted to withdraw the paper, and this preprint should not be cited as these important issues need to be clarified in a revised publication. Anesthesiology & Pain Medicine Full Text 23, February, 2024. Research Square has withdrawn this preprint as concerns have been raised about the alignment between this study and another by Shi et al. (2020) "Dexmedetomidine improves early postoperative neurocognitive disorder in elderly male patients undergoing thoracoscopic lobectomy". Experimental and Therapeutic Medicine, 20, 3868-3877 . Despite both studies citing the same clinical trial registration, they detail divergent research protocols and outcomes. Due to these significant discrepancies with the information registered for the trial, we have opted to withdraw the paper, and this preprint should not be cited as these important issues need to be clarified in a revised publication. Cite Share Download PDF Status: Posted Version 2 posted You are reading this latest preprint version Show more versions Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-127973","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":274574436,"identity":"9f81c06c-f156-41d8-804b-7390c9f4d84a","order_by":0,"name":"Na He","email":"","orcid":"","institution":"The affiliated hospital of Inner Mongolia Medical University","correspondingAuthor":false,"prefix":"","firstName":"Na","middleName":"","lastName":"He","suffix":""},{"id":274574437,"identity":"1158a77e-1d26-45e8-9859-cddd237962a5","order_by":1,"name":"Haixia Shi","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA20lEQVRIiWNgGAWjYNACgxoefvYGBgbGBqK1VByTkew5ANXCRpSWM8w2BjcSiNRiLnb86safbWw8DDffGD74uYMhj1+egOssZ+eU3ZBsk+FhnJ1jbNh7hqFYso2ALQa3c9JuGAJtYZbOMZPgbWNI3HCMGC2Jbcw8bJJnzH/+BWrZT1hL+rEbB84w8/BI8Jgxg20h5H2gLWw3GyqOAXWkFUvLtkkkzjiWQNCWZzd/GNTY2x8/vPHj2zabxP7mAwSsYeAxgDI4QAwJQspBgP0BOmMUjIJRMApGASoAACDMRoQlQaR5AAAAAElFTkSuQmCC","orcid":"","institution":"The affiliated hospital of Inner Mongolia Medical University","correspondingAuthor":true,"prefix":"","firstName":"Haixia","middleName":"","lastName":"Shi","suffix":""},{"id":274574438,"identity":"60d431b8-acd3-4a5d-886d-81de7bb752f4","order_by":2,"name":"Yajuan Hu","email":"","orcid":"","institution":"The affiliated hospital of Inner Mongolia Medical University","correspondingAuthor":false,"prefix":"","firstName":"Yajuan","middleName":"","lastName":"Hu","suffix":""},{"id":274574439,"identity":"8c0a5746-9ac5-47d5-b633-bc6d8e32cb84","order_by":3,"name":"Alberto Uribe","email":"","orcid":"","institution":"The Ohio State University Wexner Medical Center","correspondingAuthor":false,"prefix":"","firstName":"Alberto","middleName":"","lastName":"Uribe","suffix":""},{"id":274574440,"identity":"baaf1069-3762-406b-928b-8af0538ba0b5","order_by":4,"name":"Xinhua Mu","email":"","orcid":"","institution":"The affiliated hospital of Inner Mongolia Medical University","correspondingAuthor":false,"prefix":"","firstName":"Xinhua","middleName":"","lastName":"Mu","suffix":""},{"id":274574441,"identity":"1dcdc934-66b0-483e-9dd5-b2f5688fd966","order_by":5,"name":"Fei Song","email":"","orcid":"","institution":"The affiliated hospital of Inner Mongolia Medical University","correspondingAuthor":false,"prefix":"","firstName":"Fei","middleName":"","lastName":"Song","suffix":""},{"id":274574442,"identity":"5d3abb8b-f63f-4f6a-a914-65c984e91e4e","order_by":6,"name":"Jianshe Yu","email":"","orcid":"","institution":"The affiliated hospital of Inner Mongolia Medical University","correspondingAuthor":false,"prefix":"","firstName":"Jianshe","middleName":"","lastName":"Yu","suffix":""}],"badges":[],"createdAt":"2020-12-14 01:59:05","currentVersionCode":2,"declarations":"","doi":"10.21203/rs.3.rs-127973/v2","doiUrl":"https://doi.org/10.21203/rs.3.rs-127973/v2","draftVersion":[],"editorialEvents":[],"editorialNote":"\u003cp\u003e23, February, 2024. 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