Cytologic findings of atrophic endometrium cytologically diagnosed as suspicious.

In: The Journal of the Japanese Society of Clinical Cytology · 1995 · vol. 34(1) , pp. 21–26 · doi:10.5795/jjscc.34.21 · W2321089292
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This study examined cytologic findings in 27 cases of atrophic endometrium diagnosed as suspicious, noting enlarged nuclei and coarse chromatin granules were frequent, while nuclear size differed significantly between atypical and non-atypical cells.

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Abstract

内膜細胞診疑陽性例のうち, 子宮鏡および組織診で確認した萎縮内膜27例の細胞所見について検討した. 症例の平均年齢は58±6.5歳で, 23例が閉経後, 4例が閉経前であった. 細胞所見のうち核腫大, クロマチン粗大顆粒の頻度が高く, 細胞重積性, 細胞集塊辺縁不整の頻度は低かった. 萎縮内膜の異型細胞群の核最大径は9.31±2.35μmであったのに対し異型のない細胞群は7.08±1.80μmで有意に異型細胞群の核は腫大していた. 閉経5年以内と10年以上の群で異型細胞所見数が多かった. 萎縮内膜で異型細胞が出現する理由として, 内膜腺細胞の萎縮が均等に起こらないことが推測された.

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