Palpitations and Lipothymia in a Diabetic Patient: Unveiling a Mitral Myxoma

Palpitations and Lipothymia in a Diabetic Patient: Unveiling a Mitral Myxoma | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Case Report Palpitations and Lipothymia in a Diabetic Patient: Unveiling a Mitral Myxoma mehdi rochd, hamdani zainab, hajar hatim, Habbal rachida This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6908828/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Mitral myxomas are rare benign tumors that typically originate in the left atrium, with a higher prevalence in women aged 30-60 years. They can cause a wide range of symptoms, including palpitations, lipothymia, and embolic events, depending on their size, location, and mobility. Early detection and surgical resection are critical for a favorable outcome.We present the case of a 60-year-old woman with a history of hypertension and type 2 diabetes who presented with recurrent lipothymia and palpitations. Physical examination revealed sinus tachycardia at 120 bpm, with stable hemodynamics and no signs of acute decompensation. Transthoracic echocardiography revealed a mass near the mitral valve, measuring 33 mm x 22 mm, highly suggestive of a mitral myxoma. The patient underwent successful surgical resection of the mass via a median sternotomy. The procedure was uneventful, and the patient recovered well without complications. At one year after surgery, the patient was asymptomatic, with no recurrence of palpitations or lipothymia. Serial echocardiograms showed no evidence of residual tumor or mitral valve dysfunction. Her hypertension and diabetes were better controlled, contributing to her positive recovery. This case highlights the importance of considering cardiac tumors, such as mitral myxomas, in patients presenting with unexplained palpitations and lipothymia. Early diagnosis through imaging and timely surgical intervention can lead to excellent outcomes. Clinicians should be vigilant in recognizing cardiac masses, particularly in patients with predisposing cardiovascular risk factors. Figures Figure 1 Figure 2 Figure 3 Introduction A 60-year-old woman with a medical history of hypertension and type 2 diabetes presented to the cardiology clinic with complaints of recurrent lipothymia (fainting sensations) and palpitations. These symptoms had been progressively worsening over the past few months, prompting her to seek medical attention. Clinical Presentation The patient reported episodes of dizziness and a sensation of her heart racing. Her past medical history was significant for long-standing hypertension and diabetes, both of which had been poorly controlled. She had no history of previous cardiovascular events. Upon examination, she appeared well, with no significant findings on physical examination, except for a slightly elevated blood pressure of 150/90 mmHg. On physical examination, the patient appeared to be in no acute distress. Her heart rate was 120 beats per minute, regular, and consistent with sinus tachycardia. Blood pressure was elevated at 150/90 mmHg, likely due to her history of hypertension. The respiratory rate was 18 breaths per minute, within normal limits, and her temperature was 36.7°C, afebrile. Auscultation revealed regular heart sounds without murmurs, gallops, or rubs. The tachycardia was the only notable abnormality, with the first and second heart sounds audible without additional pathological sounds. There was no evidence of a pericardial friction rub. The jugular venous pressure (JVP) was normal, and there were no signs of heart failure, such as peripheral edema or cyanosis. Peripheral pulses were strong and symmetrical. On abdominal examination, there was no hepatomegaly or splenomegaly, and the patient was not tender to palpation. Pulmonary auscultation was clear without rales or wheezing. Overall, the patient’s condition appeared stable hemodynamically despite the sinus tachycardia, with no signs of acute decompensation or systemic embolism, though further investigation into the underlying cause was warranted. A transthoracic echocardiography was performed to investigate the cause of her symptoms. The results revealed a mass located in the area of the mitral valve, measuring approximately 33 mm x 22 mm. The characteristics of the mass, along with the patient's clinical presentation, raised suspicion for a mitral myxoma. Myxomas are rare benign tumors, typically located in the left atrium, and are the most common primary cardiac tumors ( 1 , 2 , 3 , 4 ). The patient was promptly referred for surgery. She underwent successful mitral valve myxoma resection via a median sternotomy. The procedure was uneventful, and there were no complications during her hospitalization. The tumor was excised in toto, and the valve was preserved. At the one-year follow-up, the patient was doing well. She had no recurrence of symptoms such as lipothymia or palpitations. Her blood pressure and diabetes were better controlled with medication adjustments, and she remained asymptomatic without any signs of mitral valve dysfunction or tumor recurrence. Serial echocardiograms showed no evidence of residual tumor or valvular complications. Discussion Mitral myxomas are the most common cardiac tumors in adults, with a peak incidence in women aged 30–60 years ( 5 , 6 ). These tumors are usually located in the left atrium but can also involve the mitral valve, as seen in this case. Clinical symptoms vary depending on the size, location, and mobility of the tumor. In this case, the patient presented with lipothymia and palpitations, which can occur due to obstruction of the mitral valve or embolic events ( 7 ). Sinus tachycardia, as observed in this patient, is often a compensatory response to these symptoms or related to secondary arrhythmias. Myxomas can also cause systemic embolism if pieces of the tumor or blood clots dislodge and travel through the circulation, potentially leading to ischemic events in other organs. However, this patient did not exhibit neurological symptoms or signs of embolism during the clinical examination, which is reassuring ( 8 ). Surgical resection remains the treatment of choice for symptomatic cardiac myxomas, with a good prognosis if the tumor is excised without complications ( 9 , 10 ). This patient underwent successful surgery with no post-operative complications and a positive outcome at one-year follow-up. The absence of residual tumor and the stable hemodynamic status of the patient at follow-up are consistent with favorable outcomes following myxoma resection. Additionally, the improved control of her hypertension and diabetes contributed to her overall good prognosis. The case highlights the importance of considering myxoma in patients with unexplained palpitations, lipothymia, or other nonspecific symptoms, particularly in the presence of predisposing factors like hypertension and diabetes. Conclusion This case emphasizes the importance of considering cardiac tumors in the differential diagnosis of unexplained symptoms like palpitations and lipothymia. Prompt diagnosis via imaging and timely surgical intervention can lead to excellent outcomes. Clinicians should remain vigilant for signs of cardiac masses, especially in patients with risk factors for cardiovascular disease. Declarations Informed consent for publication was obtained from the patient’s next of kin. References Sethi P, Bandaru V, et al. Yearlong Near‑Syncope: Presentation of a Rare Right Atrial Myxoma . Case Rep . 2024;67‑y‑year case of palpitations, dizziness and near‑syncope; 4.3 × 4.0 cm right atrial myxoma sciencedirect.com+15pmc.ncbi.nlm.nih.gov+15journals.lww.com+15. Thakur D, Sridhar A, Solomon NAG. An Unusual Presentation of Left Atrial Myxoma in an Adolescent . Int J Clin Pediatr . 2017;6(3‑4):46–50. Présentation neurologique chez une patiente jeune theijcp.org. Bandaru V, Sethi P. Case Report: A myxoma with a far reach . Frontiers Cardiovasc Med . 2024; — Palpitations et syncopes chez patiente de 73 ans avec image large dans l’oreillette gauche frontiersin.org+1pmc.ncbi.nlm.nih.gov+1. Agrawal A, et al. Extracardiac manifestations of atrial myxomas . PMC . 2017; triade obstruction‑embolie‑symptômes constitutionnels clinsurggroup.us+15pmc.ncbi.nlm.nih.gov+15sciencedirect.com+15. Pinede L, Duhaut P, Loire R. Clinical presentation of left atrial cardiac myxoma: A series of 112 consecutive cases . Medicine (Baltimore) . 2001;80(3):159–172. Série significative sur la présentation clinique theijcp.org+1clinsurggroup.us+1. Aggarwal SK, et al. Clinical presentation and investigation findings in cardiac myxomas: new insights from the developing world . Am Heart J . 2007;154(6):1102–1107. Donne détails sur palpitations et lipothymie theijcp.org+1clinsurggroup.us+1. Reynen K. Cardiac Myxomas . N Engl J Med . 1995;333(24):1610–1617. Revue classique positionnant les myxomes comme tumeurs primaires les plus fréquentes journals.lww.com+14bjcardio.co.uk+14clinsurggroup.us+14. Aggarwal SK, Barik R, Sarma TC, Iyer VR, Sai V, Mishra J, Voleti CD. Clinical presentation and investigation findings in cardiac myxomas: new insights from the developing world . Am Heart J . 2007;154(6):1102–1107. theijcp.org+1clinsurggroup.us+1. Schmermund A, et al. A pulmonary triad in a patient with a giant left atrial myxoma . Br J Cardiol . 2018; description d’un myxome géant provoquant toux‑syncope‑dyspnée bjcardio.co.uk+1academic.oup.com+1. Shah IK, Dearani JA, Daly RC, et al. Cardiac Myxomas: A 50‑year experience with resection and analysis of risk factors for recurrence . Ann Thorac Surg . 2015;100(2):495–500. Étude sur récidive post‑résection Additional Declarations The authors declare no competing interests. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6908828","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Case Report","associatedPublications":[],"authors":[{"id":472217020,"identity":"452f9bb5-cc3d-479c-985e-bb6a28ac190f","order_by":0,"name":"mehdi rochd","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAAzElEQVRIiWNgGAWjYDACdjB5gLEfRCUUEKOFGaplZgNIiwEpWjYcANHEaOFnZmD78KHmjuzm86sTPzwwYJDnFzuAX4tkMwPzzBnHnhlvu/F2swTQYYYzZyfg12JwmIGZmbfhcOK2G2c3gLQkGNwmoMUepmXzjLObfxClxYAZqmUDf+824myROMzYzDjj2GHjGTd4t1kkGEgQ9gt/e/Nhhg81h2X7+89uvvmjwkaeX5qAFgYGxgaofWCVEoSUo9h3gBTVo2AUjIJRMJIAAEFWRQDGneNtAAAAAElFTkSuQmCC","orcid":"","institution":"","correspondingAuthor":true,"prefix":"","firstName":"mehdi","middleName":"","lastName":"rochd","suffix":""},{"id":472217136,"identity":"64bbc38d-280c-48a5-ae90-b151c2325a37","order_by":1,"name":"hamdani zainab","email":"","orcid":"","institution":"","correspondingAuthor":false,"prefix":"","firstName":"hamdani","middleName":"","lastName":"zainab","suffix":""},{"id":472217137,"identity":"27369332-efd7-47e0-a9cd-54cc48c86e0d","order_by":2,"name":"hajar hatim","email":"","orcid":"","institution":"","correspondingAuthor":false,"prefix":"","firstName":"hajar","middleName":"","lastName":"hatim","suffix":""},{"id":472217138,"identity":"60fb2c15-3252-487e-81c7-c34c69e68416","order_by":3,"name":"Habbal rachida","email":"","orcid":"","institution":"","correspondingAuthor":false,"prefix":"","firstName":"Habbal","middleName":"","lastName":"rachida","suffix":""}],"badges":[],"createdAt":"2025-06-16 23:03:59","currentVersionCode":1,"declarations":{"humanSubjects":true,"vertebrateSubjects":false,"conflictsOfInterestStatement":false,"humanSubjectEthicalGuidelines":true,"humanSubjectConsent":true,"humanSubjectClinicalTrial":false,"humanSubjectCaseReport":true,"vertebrateSubjectEthicalGuidelines":false},"doi":"10.21203/rs.3.rs-6908828/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-6908828/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":85177776,"identity":"a9b1e9cd-c38c-4555-95ed-273092cd7e32","added_by":"auto","created_at":"2025-06-23 06:51:02","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":471221,"visible":true,"origin":"","legend":"\u003cp\u003eTwo-dimensional transthoracic echocardiogram demonstrating a large left atrial myxoma\u003c/p\u003e","description":"","filename":"1.png","url":"https://assets-eu.researchsquare.com/files/rs-6908828/v1/756c20536d9f01f66f9672dc.png"},{"id":85177778,"identity":"676adb47-c05e-4768-a276-d370d7252590","added_by":"auto","created_at":"2025-06-23 06:51:02","extension":"png","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":459431,"visible":true,"origin":"","legend":"\u003cp\u003eTransthoracic echocardiogram demonstrating a large left atrial myxoma. The dimensions of the mass are 3.3 cm x 2.1 cm.\u003c/p\u003e","description":"","filename":"2.png","url":"https://assets-eu.researchsquare.com/files/rs-6908828/v1/9a409d57166d7a39b4da8d38.png"},{"id":85177310,"identity":"4fa56794-bfbf-4550-ad5f-10573c720e6e","added_by":"auto","created_at":"2025-06-23 06:43:02","extension":"png","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":205007,"visible":true,"origin":"","legend":"\u003cp\u003eIntraoperative image showing the surgical resection of the cardiac myxoma.\u003c/p\u003e","description":"","filename":"3.png","url":"https://assets-eu.researchsquare.com/files/rs-6908828/v1/819f357238414b9f24e91e5f.png"},{"id":85177781,"identity":"96a23321-bf4b-420d-a0a1-d4f16cb51a54","added_by":"auto","created_at":"2025-06-23 06:51:07","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":1953645,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-6908828/v1/39e2bae4-6084-46e2-b760-cb21b0c0d808.pdf"}],"financialInterests":"The authors declare no competing interests.","formattedTitle":"\u003cp\u003ePalpitations and Lipothymia in a Diabetic Patient: Unveiling a Mitral Myxoma\u003c/p\u003e","fulltext":[{"header":"Introduction","content":"\u003cp\u003e \u003cdiv class=\"BlockQuote\"\u003e \u003cp\u003eA 60-year-old woman with a medical history of hypertension and type 2 diabetes presented to the cardiology clinic with complaints of recurrent lipothymia (fainting sensations) and palpitations. These symptoms had been progressively worsening over the past few months, prompting her to seek medical attention.\u003c/p\u003e \u003c/div\u003e \u003c/p\u003e"},{"header":"Clinical Presentation","content":"\u003cdiv class=\"BlockQuote\"\u003e\n \u003cp\u003eThe patient reported episodes of dizziness and a sensation of her heart racing. Her past medical history was significant for long-standing hypertension and diabetes, both of which had been poorly controlled. She had no history of previous cardiovascular events. Upon examination, she appeared well, with no significant findings on physical examination, except for a slightly elevated blood pressure of 150/90 mmHg.\u003c/p\u003e\n \u003cp\u003eOn physical examination, the patient appeared to be in no acute distress. Her heart rate was 120 beats per minute, regular, and consistent with sinus tachycardia. Blood pressure was elevated at 150/90 mmHg, likely due to her history of hypertension. The respiratory rate was 18 breaths per minute, within normal limits, and her temperature was 36.7\u0026deg;C, afebrile. Auscultation revealed regular heart sounds without murmurs, gallops, or rubs. The tachycardia was the only notable abnormality, with the first and second heart sounds audible without additional pathological sounds. There was no evidence of a pericardial friction rub. The jugular venous pressure (JVP) was normal, and there were no signs of heart failure, such as peripheral edema or cyanosis. Peripheral pulses were strong and symmetrical. On abdominal examination, there was no hepatomegaly or splenomegaly, and the patient was not tender to palpation. Pulmonary auscultation was clear without rales or wheezing. Overall, the patient\u0026rsquo;s condition appeared stable hemodynamically despite the sinus tachycardia, with no signs of acute decompensation or systemic embolism, though further investigation into the underlying cause was warranted.\u003c/p\u003e\n \u003cp\u003eA transthoracic echocardiography was performed to investigate the cause of her symptoms. The results revealed a mass located in the area of the mitral valve, measuring approximately 33 mm x 22 mm. The characteristics of the mass, along with the patient\u0026apos;s clinical presentation, raised suspicion for a mitral myxoma. Myxomas are rare benign tumors, typically located in the left atrium, and are the most common primary cardiac tumors (\u003cspan class=\"CitationRef\"\u003e1\u003c/span\u003e, \u003cspan class=\"CitationRef\"\u003e2\u003c/span\u003e, \u003cspan class=\"CitationRef\"\u003e3\u003c/span\u003e, \u003cspan class=\"CitationRef\"\u003e4\u003c/span\u003e).\u003c/p\u003e\n\u003c/div\u003e\n\u003cdiv class=\"BlockQuote\"\u003e\n \u003cp\u003eThe patient was promptly referred for surgery. She underwent successful mitral valve myxoma resection via a median sternotomy. The procedure was uneventful, and there were no complications during her hospitalization. The tumor was excised in toto, and the valve was preserved.\u003c/p\u003e\n \u003cp\u003eAt the one-year follow-up, the patient was doing well. She had no recurrence of symptoms such as lipothymia or palpitations. Her blood pressure and diabetes were better controlled with medication adjustments, and she remained asymptomatic without any signs of mitral valve dysfunction or tumor recurrence. Serial echocardiograms showed no evidence of residual tumor or valvular complications.\u003c/p\u003e\n\u003c/div\u003e"},{"header":"Discussion","content":"\u003cp\u003e \u003cdiv class=\"BlockQuote\"\u003e \u003cp\u003eMitral myxomas are the most common cardiac tumors in adults, with a peak incidence in women aged 30\u0026ndash;60 years (\u003cspan citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e, \u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e). These tumors are usually located in the left atrium but can also involve the mitral valve, as seen in this case. Clinical symptoms vary depending on the size, location, and mobility of the tumor. In this case, the patient presented with lipothymia and palpitations, which can occur due to obstruction of the mitral valve or embolic events (\u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e). Sinus tachycardia, as observed in this patient, is often a compensatory response to these symptoms or related to secondary arrhythmias.\u003c/p\u003e \u003cp\u003eMyxomas can also cause systemic embolism if pieces of the tumor or blood clots dislodge and travel through the circulation, potentially leading to ischemic events in other organs. However, this patient did not exhibit neurological symptoms or signs of embolism during the clinical examination, which is reassuring (\u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e). Surgical resection remains the treatment of choice for symptomatic cardiac myxomas, with a good prognosis if the tumor is excised without complications (\u003cspan citationid=\"CR9\" class=\"CitationRef\"\u003e9\u003c/span\u003e, \u003cspan citationid=\"CR10\" class=\"CitationRef\"\u003e10\u003c/span\u003e). This patient underwent successful surgery with no post-operative complications and a positive outcome at one-year follow-up.\u003c/p\u003e \u003cp\u003eThe absence of residual tumor and the stable hemodynamic status of the patient at follow-up are consistent with favorable outcomes following myxoma resection. Additionally, the improved control of her hypertension and diabetes contributed to her overall good prognosis. The case highlights the importance of considering myxoma in patients with unexplained palpitations, lipothymia, or other nonspecific symptoms, particularly in the presence of predisposing factors like hypertension and diabetes.\u003c/p\u003e \u003c/div\u003e \u003c/p\u003e"},{"header":"Conclusion","content":"\u003cp\u003e \u003cdiv class=\"BlockQuote\"\u003e \u003cp\u003eThis case emphasizes the importance of considering cardiac tumors in the differential diagnosis of unexplained symptoms like palpitations and lipothymia. Prompt diagnosis via imaging and timely surgical intervention can lead to excellent outcomes. Clinicians should remain vigilant for signs of cardiac masses, especially in patients with risk factors for cardiovascular disease.\u003c/p\u003e \u003c/div\u003e \u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cspan\u003eInformed consent for publication was obtained from the patient\u0026rsquo;s next of kin.\u003c/span\u003e\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n\u003cli\u003eSethi P, Bandaru V, et al. \u003cstrong\u003eYearlong Near‑Syncope: Presentation of a Rare Right Atrial Myxoma\u003c/strong\u003e. \u003cem\u003eCase Rep\u003c/em\u003e. 2024;67‑y‑year case of palpitations, dizziness and near‑syncope; 4.3 \u0026times; 4.0 cm right atrial myxoma sciencedirect.com+15pmc.ncbi.nlm.nih.gov+15journals.lww.com+15.\u003c/li\u003e\n\u003cli\u003eThakur D, Sridhar A, Solomon NAG. \u003cstrong\u003eAn Unusual Presentation of Left Atrial Myxoma in an Adolescent\u003c/strong\u003e. \u003cem\u003eInt J Clin Pediatr\u003c/em\u003e. 2017;6(3‑4):46\u0026ndash;50. Pr\u0026eacute;sentation neurologique chez une patiente jeune theijcp.org.\u003c/li\u003e\n\u003cli\u003eBandaru V, Sethi P. \u003cstrong\u003eCase Report: A myxoma with a far reach\u003c/strong\u003e. \u003cem\u003eFrontiers Cardiovasc Med\u003c/em\u003e. 2024; \u0026mdash; Palpitations et syncopes chez patiente de 73 ans avec image large dans l\u0026rsquo;oreillette gauche frontiersin.org+1pmc.ncbi.nlm.nih.gov+1.\u003c/li\u003e\n\u003cli\u003eAgrawal A, et al. \u003cstrong\u003eExtracardiac manifestations of atrial myxomas\u003c/strong\u003e. \u003cem\u003ePMC\u003c/em\u003e. 2017; triade obstruction‑embolie‑sympt\u0026ocirc;mes constitutionnels clinsurggroup.us+15pmc.ncbi.nlm.nih.gov+15sciencedirect.com+15.\u003c/li\u003e\n\u003cli\u003ePinede L, Duhaut P, Loire R. \u003cstrong\u003eClinical presentation of left atrial cardiac myxoma: A series of 112 consecutive cases\u003c/strong\u003e. \u003cem\u003eMedicine (Baltimore)\u003c/em\u003e. 2001;80(3):159\u0026ndash;172. S\u0026eacute;rie significative sur la pr\u0026eacute;sentation clinique theijcp.org+1clinsurggroup.us+1.\u003c/li\u003e\n\u003cli\u003eAggarwal SK, et al. \u003cstrong\u003eClinical presentation and investigation findings in cardiac myxomas: new insights from the developing world\u003c/strong\u003e. \u003cem\u003eAm Heart J\u003c/em\u003e. 2007;154(6):1102\u0026ndash;1107. Donne d\u0026eacute;tails sur palpitations et lipothymie theijcp.org+1clinsurggroup.us+1.\u003c/li\u003e\n\u003cli\u003eReynen K. \u003cstrong\u003eCardiac Myxomas\u003c/strong\u003e. \u003cem\u003eN Engl J Med\u003c/em\u003e. 1995;333(24):1610\u0026ndash;1617. Revue classique positionnant les myxomes comme tumeurs primaires les plus fr\u0026eacute;quentes journals.lww.com+14bjcardio.co.uk+14clinsurggroup.us+14.\u003c/li\u003e\n\u003cli\u003eAggarwal SK, Barik R, Sarma TC, Iyer VR, Sai V, Mishra J, Voleti CD. \u003cstrong\u003eClinical presentation and investigation findings in cardiac myxomas: new insights from the developing world\u003c/strong\u003e. \u003cem\u003eAm Heart J\u003c/em\u003e. 2007;154(6):1102\u0026ndash;1107. theijcp.org+1clinsurggroup.us+1.\u003c/li\u003e\n\u003cli\u003eSchmermund A, et al. \u003cstrong\u003eA pulmonary triad in a patient with a giant left atrial myxoma\u003c/strong\u003e. \u003cem\u003eBr J Cardiol\u003c/em\u003e. 2018; description d\u0026rsquo;un myxome g\u0026eacute;ant provoquant toux‑syncope‑dyspn\u0026eacute;e bjcardio.co.uk+1academic.oup.com+1.\u003c/li\u003e\n\u003cli\u003eShah IK, Dearani JA, Daly RC, et al. \u003cstrong\u003eCardiac Myxomas: A 50‑year experience with resection and analysis of risk factors for recurrence\u003c/strong\u003e. \u003cem\u003eAnn Thorac Surg\u003c/em\u003e. 2015;100(2):495\u0026ndash;500. \u0026Eacute;tude sur r\u0026eacute;cidive post‑r\u0026eacute;section\u003c/li\u003e\n\u003c/ol\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"","lastPublishedDoi":"10.21203/rs.3.rs-6908828/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-6908828/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eMitral myxomas are rare benign tumors that typically originate in the left atrium, with a higher prevalence in women aged 30-60 years. They can cause a wide range of symptoms, including palpitations, lipothymia, and embolic events, depending on their size, location, and mobility. Early detection and surgical resection are critical for a favorable outcome.We present the case of a 60-year-old woman with a history of hypertension and type 2 diabetes who presented with recurrent lipothymia and palpitations. Physical examination revealed sinus tachycardia at 120 bpm, with stable hemodynamics and no signs of acute decompensation. Transthoracic echocardiography revealed a mass near the mitral valve, measuring 33 mm x 22 mm, highly suggestive of a mitral myxoma. The patient underwent successful surgical resection of the mass via a median sternotomy. The procedure was uneventful, and the patient recovered well without complications.\u003cbr\u003e\nAt one year after surgery, the patient was asymptomatic, with no recurrence of palpitations or lipothymia. Serial echocardiograms showed no evidence of residual tumor or mitral valve dysfunction. Her hypertension and diabetes were better controlled, contributing to her positive recovery.\u003cbr\u003e\nThis case highlights the importance of considering cardiac tumors, such as mitral myxomas, in patients presenting with unexplained palpitations and lipothymia. Early diagnosis through imaging and timely surgical intervention can lead to excellent outcomes. Clinicians should be vigilant in recognizing cardiac masses, particularly in patients with predisposing cardiovascular risk factors.\u003c/p\u003e","manuscriptTitle":"Palpitations and Lipothymia in a Diabetic Patient: Unveiling a Mitral Myxoma","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-06-23 06:42:57","doi":"10.21203/rs.3.rs-6908828/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"63461448-b86e-4e27-92fd-122a4f2c797a","owner":[],"postedDate":"June 23rd, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2025-06-23T06:42:57+00:00","versionOfRecord":[],"versionCreatedAt":"2025-06-23 06:42:57","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-6908828","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-6908828","identity":"rs-6908828","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}