Menstrual Disorders Related to Endocrine Diseases

Costanzo Moretti
In: Endocrinology · 2020 · pp. 1–21 · doi:10.1007/978-3-030-03594-5_4-1 · W3008851399
book-chapter OA: closed CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-08 ⓘ

This report examines how neuroendocrine, pituitary, adrenal, thyroid, and other pathologies influence the female reproductive axis, affecting hormonal feedback and causing menstrual disorders.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-08 ⓘ

This paper reviews how neuroendocrine, pituitary, adrenal, thyroid, and other local/systemic pathologies disrupt the female reproductive axis, focusing on mechanisms that interfere with the coordinated hormonal feedback loops controlling normal menstruation and fertility. It synthesizes evidence that endocrine disorders can alter steroidal and nonsteroidal hormones, including endometrial paracrine, autocrine, and intracrine factors, with hypothalamic and pituitary dysfunction highlighted as major drivers of abnormal uterine bleeding. The caveat is that it is a high-level narrative/overview rather than a single new study, so it does not provide original data or quantify effects in specific patient groups. Relevance to endometriosis: the paper discusses menstruation and endometrial intracrinology mechanisms that underpin menstrual disorders, which are foundational for understanding endometriosis-associated abnormal uterine bleeding, though endometriosis is not explicitly examined as a separate disease focus.

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last seen: 2026-06-10T17:14:06.276822+00:00
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