Effect of danazol on the radiographic density of breast parenchyma

D Ouimet-Oliva, J Van Campenhout, Van Campenhout J, G Hébert, G A Hébert, Jacques Ladouceur, J Ladouceur
Journal of the Canadian Association of Radiologists · 1981 · vol. 32(3) , pp. 159–61 · PMID:7298699 · W2403464197
Non-randomised trial OA: closed CC0 ⤵ 3 in-corpus citations
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Danazol treatment reduced breast volume and density in women with mammary dysplasia, facilitating clearer mammographic visualization of the parenchyma.

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Abstract

We have given danazol to 25 women with mammary dysplasia. Clinical, cytologic and radiographic examinations were made before, during and after this treatment. In 23 patients breast pain disappeared completely. Danazol produced such a decrease in breast volume and density that on the mammogram the parenchyma was much more easily visualized. We suggest that danazol might be given before mammography to high risk women having dense dysplasic breasts, in order to ensure easier and more accurate interpretation.

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MeSH descriptors

Breast Diseases Danazol Fibrocystic Breast Disease Pregnadienes Adult Breast Diseases Danazol Danazol Female Fibrocystic Breast Disease Fibrocystic Breast Disease Humans Mammography Middle Aged Pregnadienes Radiographic Image Enhancement

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