A Very Rare Case of Ovarian Collision Tumor with Contralateral Endometriotic Cyst: Fertility-Sparing Surgical Management

Venkata Sujatha Vellanki, Ravi Kanth Kongara, Sarath Gillellamudi, Udaya Lakshmi k, Anupama Mikkilineni
2026 · doi:10.5281/zenodo.18501151 · W7128231644
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This case report describes a 25-year-old woman presenting with progressive abdominal distension and a large complex ovarian mass. Laparoscopic surgery revealed a rare unilateral ovarian collision tumor consisting of a serous cystadenoma and a mature cystic teratoma, alongside a contralateral endometriotic cyst. Histopathology confirmed the distinct neoplasms without interaction, and the patient recovered fully with preserved ovarian function after fertility-sparing excision. This paper is centrally about endometriosis — specifically, it documents a concurrent endometriotic cyst in the context of a rare ovarian collision tumor.

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Abstract

Abstract Ovarian collision tumors are rare entities where two histologically distinct neoplasms coexist in the same ovary without interaction, often mimicking malignancy. Fertility-sparing surgery is crucial in young women. We present a unique case of a 25-year-old woman with progressive abdominal distension. Imaging revealed a large complex mass. Laparoscopic fertility-preserving surgery uncovered a 30 cm serous cystadenoma and a 5-7 cm mature cystic teratoma in the right ovary, along with a 4x5 cm endometriotic cyst in the contralateral ovary. A total of 12.5 litres of f luid was aspirated. Histopathology confirmed a collision tumor. Postoperatively, the patient experienced transient difficulty walking due to a sudden 12 kg weight loss but recovered fully with preserved ovarian function. This is the first reported case of a unilateral ovarian collision tumor with a contralateral endometriotic cyst. The case emphasizes the importance of considering collision tumors in differential diagnoses and the efficacy of laparoscopic fertility-sparing approaches.
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A Very Rare Case of Ovarian Collision Tumor with Contralateral Endometriotic Cyst: Fertility-Sparing Surgical Management Authors/Creators - 1. Oasis Fertility, Vijayawada, Andhra Pradesh, India - 2. Ravi Hospital, Vijayawada, Andhra Pradesh, India - 3. Alluri Sitarama Raju Academy of Medical Sciences, Malkapuram, Andhra Pradesh, India - 4. Anuhya Diagnostics, Vijayawada, Andhra Pradesh. India Description Abstract Ovarian collision tumors are rare entities where two histologically distinct neoplasms coexist in the same ovary without interaction, often mimicking malignancy. Fertility-sparing surgery is crucial in young women. We present a unique case of a 25-year-old woman with progressive abdominal distension. Imaging revealed a large complex mass. Laparoscopic fertility-preserving surgery uncovered a 30 cm serous cystadenoma and a 5-7 cm mature cystic teratoma in the right ovary, along with a 4x5 cm endometriotic cyst in the contralateral ovary. A total of 12.5 litres of f luid was aspirated. Histopathology confirmed a collision tumor. Postoperatively, the patient experienced transient difficulty walking due to a sudden 12 kg weight loss but recovered fully with preserved ovarian function. This is the first reported case of a unilateral ovarian collision tumor with a contralateral endometriotic cyst. The case emphasizes the importance of considering collision tumors in differential diagnoses and the efficacy of laparoscopic fertility-sparing approaches. Files wjog.2026.a3105.pdf Files (365.6 kB) | Name | Size | Download all | |---|---|---| | md5:15f7ecc9b3e96db4c0f51a0ad7da8da4 | 365.6 kB | Preview Download | Additional details Identifiers Dates - Submitted - 2026-01-07 - Accepted - 2026-01-29 - Available - 2026-01-31

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