The Silent Potassium Avalanche: Unchecking Preoperative Hypokalemia Leading to Perioperative Cardiac Arrest in an Insulin-Treated Diabetic Patient Undergoing a Whipple Procedure: A Case Report

The Silent Potassium Avalanche: Unchecking Preoperative Hypokalemia Leading to Perioperative Cardiac Arrest in an Insulin-Treated Diabetic Patient Undergoing a Whipple Procedure: A Case Report | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Case Report The Silent Potassium Avalanche: Unchecking Preoperative Hypokalemia Leading to Perioperative Cardiac Arrest in an Insulin-Treated Diabetic Patient Undergoing a Whipple Procedure: A Case Report Weiyu Han, Chunhui Gao, Ranzun Zhao This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-7184221/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 28 Nov, 2025 Read the published version in BMC Anesthesiology → Version 1 posted 14 You are reading this latest preprint version Abstract Background: Pancreaticoduodenectomy(Whipple procedure) isa highly complex abdominal surgical procedure, and while perioperative cardiac arrest is infrequent, it is associated with significant morbidity. The established risk factors for postoperative cardiac arrest includehypovolemia, acidosis, and electrolyte imbalances. Case presentation: We present the case of a 67-year-old female with a history of type 1 diabetes mellitus and hypertension who underwent a Whipple procedure under general anesthesia. Preoperative serum potassium levels, which were measured three days prior, were within normal limits (5.28 mmol/L). However, profound hypokalemia (2.71 mmol/L) was detected before the skin incision, and the anesthesiologisttreated the patient with 2 g (26.8 mEq) of intravenous potassium chloride under cardiac output monitoring. The posttreatment serum potassium level at 16:41 was 3.28 mmol/L, indicating persistent hypokalemia. Following the procedure, the patient's vital signs stabilized, meeting the criteria for transfer to the general ward. However, within 30 minutes of ward arrival, the patient experienced a sudden episode of hypertension and tachycardia, rapidly progressing to pulseless electrical activity (PEA) cardiac arrest. Immediate resuscitation efforts, including continuous cardiopulmonary resuscitation (CPR) and epinephrine administration, were initiated. After spontaneous circulation returned, the patient was transferred to the intensive care unit (ICU) and subsequently diagnosed with hypoxic-ischemicencephalopathy (HIE), multiple organ dysfunction syndrome (MODS), or sepsis. Ultimately, the patient succumbed to these complications on day 14 of ICU admission. Conclusions: This critical event underscores the vital importance of meticulous perioperative potassium management in diabetic patients undergoing major abdominal surgery. We advocate for mandatory reevaluation of electrolyte levels within 24 hours preoperatively, particularly following bowel preparation and dietary restriction, in conjunction with prophylactic potassium supplementation and careful insulin administration, as crucial measures to prevent such devastating outcomes. Perioperative Anesthesia Cardiac arrest Hypokalemia Whipple procedure Hypoxic-ischemic encephalopathy (HIE) Multiple organ dysfunction (MODS) Figures Figure 1 Figure 2 1. Background The Whipple procedure presents considerable technical challenges due to the intricate retroperitoneal anatomy surrounding the pancreas and duodenum, including proximity to major vasculature and biliary‒pancreatic ducts [ 1 ] . Elevated rates of mortality and postoperative myocardial infarction have been reported following Whipple surgery in elderly patients [ 2 ] . While advancements in preoperative assessment and intraoperative techniques have improved safety, perioperative cardiac arrest remains a rare but devastating complication. These events are frequently multifactorial, resulting from the complex interplay of surgical stress, hemodynamic instability, and acute metabolic derangements. Among modifiable risk factors, profound hypokalemia represents a critical and potentially preventable trigger for malignant arrhythmias and subsequent cardiac arrest [ 3 ] . This risk is particularly relevant in insulin-treated diabetic patients, where potassium homeostasis is often precarious. Insulin administration promotes intracellular potassium shifts, whereas common preoperative practices such as mechanical bowel preparation can induce significant potassium depletion. Despite routine electrolyte monitoring, rapid and undetected hypokalemia can develop subclinically within a short period. While the literature emphasizes the arrhythmogenic potential of hypokalemia, comprehensive documentation of its precipitous perioperative evolution in high-risk diabetic patients, particularly those who are undergoing major abdominal surgery, remains limited. Few reports detail the synergistic mechanisms (insulin effect and bowel preparation) and kinetic progression from normokalemia to life-threatening levels before cardiac arrest. This report presents a compelling case of unaddressed preoperative hypokalemia in an insulin-dependent diabetic patient undergoing elective Whipple surgery. Within 72 hours, a cascade of bowel preparation-induced losses and insulin-mediated transcellular shifts precipitated a decline from normokalemia (5.28 mmol/L) to critical hypokalemia (2.71 mmol/L), undetected by standard monitoring intervals. This rapid electrolyte imbalance culminated in postoperative cardiac arrest, resulting in HIE and MODS. Underscoring the necessity for intensified perioperative electrolyte monitoring in high-risk cohorts. 2. Case Presentation A 67-year-old female (ASA II) with well-controlled hypertension and type 1 diabetes mellitus was admitted for management of an ampullary tumor and scheduled for laparoscopic pancreaticoduodenectomy. General anesthesia was induced at 08:05 on May 29 with endotracheal intubation utilizing sufentanil, cipepofol‌, and rocuronium. Mechanical ventilation was initiated with 100% oxygen in pressure‒volume control mode, targeting a tidal volume of 7 ml/kg. Standard noninvasive monitoring and invasive arterial blood pressure monitoring methods were established. A serum potassium level measured at 08:50 revealed critical hypokalemia (2.71 mmol/L). Consequently, 2 g (26.8 mEq) of potassium chloride was administered intravenously via a central venous line over 6 hours. Remifentanil, cipepofol, sevoflurane and rocuronium were used for intraoperative anesthesia maintenance. The patient underwent a laparoscopic Whipple procedure with resection of the pancreatic head, duodenum, distal stomach, common bile duct, and gallbladder. Intraoperative blood loss was minimal (100 mL). During the 6-hour 40-minute procedure (10:20), the serum potassium level measured at 16:41 was 3.28 mmol/L. The procedure ended at 17:00. After tracheal extubation at 17:25 in the postanesthesia care unit (PACU), the patient remained stable and was transferred to the ward at 17:50. At 18:19, the patient acutely developed hypertension, tachycardia, and new-onset arrhythmias. The rapid decline in potassium levels directly precipitated refractory ventricular arrhythmias and cardiac arrest. Cardiac arrest occurred at 18:35, prompting immediate CPR with intravenous epinephrine. Intensive care physicians performed endotracheal intubation and manual ventilation. Defibrillator monitoring revealed PEA, a nonshockable rhythm. Following continued CPR, spontaneous circulation returned at 18:58, with sinus tachycardia (150–170 bpm), hypertension (167/121 mmHg), and a peripheral oxygen saturation of 98%. Bilateral pupillary dilation (5.5 mm) with an absent light reflex was noted. The patient was transferred to the ICU for mechanical ventilation and hemodynamic support. Comprehensive ICU care included potassium repletion, mechanical ventilation, neuroprotection (hypothermia, osmotherapy), hemodynamic support (vasodilators, vasopressors, inotropes), infection control (antibiotics), organ-specific therapies (corticosteroids, cardioprotectives, neurotrophic factors, renal preservation), nutrition, and homeostasis maintenance. Subsequent delays in identifying and correcting concurrent hypocalcemia likely compounded myocardial injury. The changes in the serum potassium and ionized calcium levels on the day of cardiac arrest and after surgery are shown in Fig. 1A-B. The patient underwent neurosurgical intervention, with a subsequent diagnosis of HIE complicated by concurrent cardiac, hepatic, and renal dysfunction. Despite aggressive multidisciplinary management (involving cardiology, neurosurgery, and the intensive care unit (ICU)), the patient failed to regain full consciousness and progressed to deep coma. Sulcal effacement in the frontal regions, consistent with cerebral edema, was observed via cranial computed tomography (CT) (Fig. 1C). Figure 1. Serum electrolyte dynamics and evolution of brain edema following cardiac arrest. (A) Serial serum potassium and calcium levels postcardiac arrest. (B-C) Brain edema progression on Day 1 and Day 6 postarrest. A notable aspect of this case was the presence of refractory hypokalemia, requiring substantially higher doses of potassium supplementation to maintain unstable potassium levels. A total of 33.5 g (448.9 mEq) of potassium chloride (including 2 g used in the operating room) and 34.2 g (200 mEq) of potassium aspartate injection were administered in the ICU. The changes in refractory hypokalemia from the beginning of anesthesia to death are shown in Table 1. Persistent elevation of myoglobin (MYO) and high-sensitivity cardiac troponin I (hs-cTnI) following resuscitation indicated ongoing myocardial injury and necrosis. Moreover, the sustained increase in N-terminal pro-B-type natriuretic peptide (NT-proBNP) suggested significant cardiac dysfunction and ventricular wall stress. Although initial therapeutic interventions transiently reduced biomarker levels, the subsequent rebound and refractoriness to intensified management indicated progressive myocardial damage and worsening cardiac function. The patient also presented with intermittent seizures and nonsustained ventricular tachycardia [ 4 ] , presented with fixed and dilated pupils (5 mm bilaterally) without light or corneal reflexes, and remained ventilator dependent. By day 14 postcardiac arrest, vital signs remained unstable (heart rate persistently > 130 bpm, systolic blood pressure < 90 mmHg, diastolic < 60 mmHg). Following discussion, the family opted for the withdrawal of life-sustaining therapies, and the patient expired. The sequence of events and management of cardiac arrest are summarized in Fig. 2 . Table 1. Serial cardiac markers, blood gases, and hypokalemia recovery relative to cumulative potassium supplementation from anesthetic induction until death. 3. Discussion and conclusions This case illustrates fatal cardiac arrest precipitated by hypokalemia during the perioperative period. Despite aggressive resuscitation efforts, the patient succumbed to MODS, HIE, and sepsis, a cascade initiated by multifactorial pathophysiological processes, including perioperative electrolyte derangements, ischemic-reperfusion injury, and metabolic dysregulation. The primary trigger for postoperative cardiac arrest was unaddressed perioperative hypokalemia. More than two enemas throughout the body are considered risk factors for hypokalemia [ 5 ] . This rapid decline was synergistically driven by insulin-mediated transcellular potassium shifts and substantial gastrointestinal potassium losses from preoperative mechanical bowel preparation. Furthermore, dietary restriction combined with sustained insulin therapy markedly potentiated this effect. Postarrest hypocalcemia exacerbates myocardial dysfunction and cerebral injury. Calcium dysregulation in cerebral ischemia‒reperfusion activates calpain-caspase apoptotic pathways, contributing to irreversible neurological injury. Exaggerated inflammatory responses, coupled with catecholamine hyperactivity, are recognized as drivers of hypocalcemia [ 6 ] . While the 7-hour operative duration was within the expected limits for Whipple procedures, prolonged anesthesia and surgical trauma precipitated a systemic inflammatory response, occult hypoperfusion, insulin resistance, and stress hyperglycemia (29.4 mmol/L at the time of arrest). Hyperglycemia potentiates oxidative stress-mediated brain injury, particularly in diabetic patients [ 7 ] . Nonetheless, we acknowledge the limitations of this report. First, regarding hypokalemia, electrolytes were not re-evaluated within 24 hours preceding the operation. Moreover, severe hypokalemia was identified intraoperatively but was not adequately corrected during the perioperative period, and delayed intervention may have contributed to arrhythmia. Second, the patient's preexisting hypertension and diabetes, although managed with medication, may have led to unrecognized microvascular dysfunction, potentially exacerbating ischemic injury following cardiac arrest [ 8 ] . Hypertension requiring medication is independently associated with cardiovascular complications after Whipple procedures and may need to be considered in preoperative risk stratification [ 9 ] . Third, although HIE was diagnosed, advanced neurological monitoring (such as electroencephalography) was not conducted, which may have resulted in underestimation of the severity of brain damage. These limitations highlight the need for prospective studies incorporating rigorous intraoperative monitoring and standardized post arrest care pathways in high-risk surgeries. In conclusion, this case report clearly illustrates the catastrophic consequences of inadequately managed perioperative hypokalemia, particularly in insulin-treated diabetic patients undergoing major abdominal surgery, such as the Whipple procedure. This fatal event underscores critical lessons. First, high-risk patients (insulin-treated diabetic patients undergoing major surgery) require serial perioperative potassium monitoring: postbowel preparation, preoperatively on the morning of surgery, immediately upon arrival at the operating room, and intraoperatively every 60 minutes for procedures exceeding 5 hours. Proactive repletion should target a preoperative potassium > 4.0 mmol/L. If necessary, surgery should be postponed until the internal environment is optimized. Second, therapeutic hypothermia represents one of the most widely implemented neuroprotective strategies following cardiac arrest [ 10 ] . The implementation of targeted temperature management (TTM) should be considered, and hyperbaric oxygen therapy may also be considered within 6 hours postarrest to mitigate HIE progression. The fatal trajectory of persistent HIE, irreversible MODS, and sepsis underscores the devastating potential of perioperative electrolyte instability in elderly patients with diminished physiological reserves. Future research must prioritize the development of validated risk stratification tools and the implementation of rigorous, protocol-driven perioperative electrolyte management strategies, especially for high-risk populations undergoing complex surgical procedures. Abbreviations PEA pulseless electrical activity CPR cardiopulmonary resuscitation ICU intensive care unit HIE hypoxic-ischemic encephalopathy MODS multiple organ disfunction PACU postanesthesia care unit CT computed tomography MYO myoglobin hs-cTnI high-sensitivity cardiac troponin I NT-proBNP N-terminal pro-B-type natriuretic peptide TTM targeted temperature management Declarations Ethics approval and consent to participate Ethical approval for this case report was officially waived by the Medical Ethics Committee of Guangzhou Medical University Cancer Center. This waiver is consistent with institutional policies and international guidelines for retrospective analysis of anonymized single-patient cases intended for educational purposes. The written informed consent form discloses anonymous medical details from the legally authorized representative of the patient's family. All procedures adhered to the principles of the Declaration of Helsinki. Consent for publication Written informed consent was obtained from the patient for publication of this case report and the accompanying data. Competing interests The authors declare that they have no competing interests. Funding Not applicable. Author Contribution WH and CG wrote the main manuscript text and prepared the figures and table. RZ contributed to manuscript revisions and supervision of the manuscript. All authors reviewed the manuscript. Acknowledgments Not applicable. Availability of data and materials The data generated and analyzed during the current case are not publicly available to protect patient privacy, but they are available from the corresponding author upon reasonable request. References Smith EB, Hardart R. Pancreaticoduodenectomy (Whipple Procedure) in a Toddler: An Anesthesia Case Report. A A Pract. 2019. 13(8): 303–5. Hakakian D, Bellaire AJ, Elsawwah JK, Harrison LE, Rolandelli RH, Nemeth ZH. Risk Factors and Surgical Outcomes of Older Adult Patients Undergoing a Whipple Procedure. South Med J. 2025;118(3):184–8. Casey B 3rd, Hofstrand R, Patel D, Bahekar A, Chapa-Rodriguez A. Hypokalemia-Induced Cardiac Arrest Cureus. 2023;15(2):e35034. Bhellum P, Angirekula S, Kumar Rohila A, Sharma A, Gupta A, Mathur N. Novel TRPM3 missense mutation leading to severe hypocalcemia presenting as seizures and complicated by non-sustained ventricular tachycardia: A case report. Qatar Med J. 2025;2025(1):28. Wang BB, Hu L, Hu XY, Han D, Wu J. Risk Factors Asscociated with Hypokalemia during Postanesthesia Recovery and Its Impact on Outcomes in Gynecological Patients: A Propensity Score Matching Study. Curr Med Sci. 2024;44(2):441–9. Melchers M, Moonen H, Breeman TM, van Bree S, van Zanten A. Parenteral calcium administration and outcomes in critically ill patients with hypocalcemia: A retrospective cohort study. J Intensive Med. 2025;5(2):151–9. Long C, Pu Y, Keng S, Tao J, Zhang B, Yue R. Novel Insights into the Mechanism and Treatment of Diabetes-Related Brain Complications: Focusing on the Blood-Brain Barrier Impairment. Aging Dis. 2025. Gazivoda VP, Greenbaum A, Beier MA, et al. Pancreatoduodenectomy: the Metabolic Syndrome is Associated with Preventable Morbidity and Mortality. J Gastrointest Surg. 2022;26(10):2167–75. Lin JJ, Conroy PC, Romero-Hernandez F, et al. Hypertension Requiring Medication Use: a Silent Predictor of Poor Outcomes After Pancreaticoduodenectomy. J Gastrointest Surg. 2023;27(2):328–36. Perkins GD, Neumar R, Hsu CH et al. Improving Outcomes After Post-Cardiac Arrest Brain Injury: A Scientific Statement from the International Liaison Committee on Resuscitation. Circulation. 2024. Additional Declarations No competing interests reported. Cite Share Download PDF Status: Published Journal Publication published 28 Nov, 2025 Read the published version in BMC Anesthesiology → Version 1 posted Editorial decision: Revision requested 10 Sep, 2025 Reviews received at journal 07 Sep, 2025 Reviewers agreed at journal 07 Sep, 2025 Reviewers agreed at journal 05 Sep, 2025 Reviews received at journal 22 Aug, 2025 Reviews received at journal 15 Aug, 2025 Reviewers agreed at journal 12 Aug, 2025 Reviewers agreed at journal 12 Aug, 2025 Reviewers agreed at journal 12 Aug, 2025 Reviewers invited by journal 05 Aug, 2025 Editor invited by journal 04 Aug, 2025 Editor assigned by journal 30 Jul, 2025 Submission checks completed at journal 30 Jul, 2025 First submitted to journal 22 Jul, 2025 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-7184221","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Case Report","associatedPublications":[],"authors":[{"id":495905700,"identity":"09b1da0b-b93b-46b3-aa84-acceecb9b0f1","order_by":0,"name":"Weiyu Han","email":"","orcid":"","institution":"Affiliated Cancer Hospital of Guangzhou Medical University","correspondingAuthor":false,"prefix":"","firstName":"Weiyu","middleName":"","lastName":"Han","suffix":""},{"id":495905703,"identity":"6e3605eb-a31a-4be9-8aad-b9cb66013686","order_by":1,"name":"Chunhui Gao","email":"","orcid":"","institution":"Affiliated Cancer Hospital of Guangzhou Medical University","correspondingAuthor":false,"prefix":"","firstName":"Chunhui","middleName":"","lastName":"Gao","suffix":""},{"id":495905704,"identity":"ffd61344-68ec-46d6-850b-2318c5201171","order_by":2,"name":"Ranzun Zhao","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAAtklEQVRIiWNgGAWjYBACCQYGZgaGCgk5NvbmA6RoOWNjzMdzLIEELYxtaYnzJHIUiNMi2d5jbPDhzOH0NoYcBoYfFdsIa5HmOWOcOKPicG4bw9kDjD1nbhPWIieRY3yY5wxQC2NfAjNjG7Fa/rYdTmdj5jEgTos0UEsy0PsJbGzEapHsOVZs2HPGxrCNhy3hIFF+kTjevFniR4WEvPz8xwcf/KggQgsKOECi+lEwCkbBKBgFuAAAfCc5b6Su7W4AAAAASUVORK5CYII=","orcid":"","institution":"Affiliated Hospital of Zunyi Medical University","correspondingAuthor":true,"prefix":"","firstName":"Ranzun","middleName":"","lastName":"Zhao","suffix":""}],"badges":[],"createdAt":"2025-07-22 08:08:09","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-7184221/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-7184221/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.1186/s12871-025-03481-5","type":"published","date":"2025-11-28T15:58:36+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":88643926,"identity":"bb5e61a7-6ba6-4a3f-92b9-5d8e643bb4da","added_by":"auto","created_at":"2025-08-08 16:18:27","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":382803,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eSerum electrolyte dynamics and evolution of brain edema following cardiac arrest.\u003c/strong\u003e\u003cbr\u003e\n(A) Serial serum potassium and calcium levels postcardiac arrest. (B-C) Brain edema progression on Day 1 and Day 6 postarrest.\u003c/p\u003e","description":"","filename":"1.png","url":"https://assets-eu.researchsquare.com/files/rs-7184221/v1/7eede714c8e2dc868aae1e97.png"},{"id":88645558,"identity":"1d9704ac-9665-470d-a2de-19b9da7268db","added_by":"auto","created_at":"2025-08-08 16:26:27","extension":"png","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":192571,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eThe whole process of the occurrence and treatment of cardiac arrest.\u003c/strong\u003e\u003c/p\u003e","description":"","filename":"2.png","url":"https://assets-eu.researchsquare.com/files/rs-7184221/v1/7b0f3278d8729da58a5672fd.png"},{"id":97179247,"identity":"ed375ea2-e4a7-410c-a5c3-02072bf3fe36","added_by":"auto","created_at":"2025-12-01 16:14:21","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":1181369,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-7184221/v1/d6271c71-0a1f-4c82-9c55-7bb2b6368b01.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"The Silent Potassium Avalanche: Unchecking Preoperative Hypokalemia Leading to Perioperative Cardiac Arrest in an Insulin-Treated Diabetic Patient Undergoing a Whipple Procedure: A Case Report","fulltext":[{"header":"1. Background","content":"\u003cp\u003e\u003cb\u003eThe\u003c/b\u003e Whipple procedure presents considerable technical challenges due to the intricate retroperitoneal anatomy surrounding the pancreas and duodenum, including proximity to major vasculature and biliary‒pancreatic ducts\u003csup\u003e[\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e]\u003c/sup\u003e. Elevated rates of mortality and postoperative myocardial infarction have been reported following Whipple surgery in elderly patients\u003csup\u003e[\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e]\u003c/sup\u003e. While advancements in preoperative assessment and intraoperative techniques have improved safety, perioperative cardiac arrest remains a rare but devastating complication. These events are frequently multifactorial, resulting from the complex interplay of surgical stress, hemodynamic instability, and acute metabolic derangements. Among modifiable risk factors, profound hypokalemia represents a critical and potentially preventable trigger for malignant arrhythmias and subsequent cardiac arrest\u003csup\u003e[\u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e]\u003c/sup\u003e. This risk is particularly relevant in insulin-treated diabetic patients, where potassium homeostasis is often precarious. Insulin administration promotes intracellular potassium shifts, whereas common preoperative practices such as mechanical bowel preparation can induce significant potassium depletion. Despite routine electrolyte monitoring, rapid and undetected hypokalemia can develop subclinically within a short period. While the literature emphasizes the arrhythmogenic potential of hypokalemia, comprehensive documentation of its precipitous perioperative evolution in high-risk diabetic patients, particularly those who are undergoing major abdominal surgery, remains limited. Few reports detail the synergistic mechanisms (insulin effect and bowel preparation) and kinetic progression from normokalemia to life-threatening levels before cardiac arrest. This report presents a compelling case of unaddressed preoperative hypokalemia in an insulin-dependent diabetic patient undergoing elective Whipple surgery. Within 72 hours, a cascade of bowel preparation-induced losses and insulin-mediated transcellular shifts precipitated a decline from normokalemia (5.28 mmol/L) to critical hypokalemia (2.71 mmol/L), undetected by standard monitoring intervals. This rapid electrolyte imbalance culminated in postoperative cardiac arrest, resulting in HIE and MODS. Underscoring the necessity for intensified perioperative electrolyte monitoring in high-risk cohorts.\u003c/p\u003e"},{"header":"2. Case Presentation","content":"\u003cp\u003eA 67-year-old female (ASA II) with well-controlled hypertension and type 1 diabetes mellitus was admitted for management of an ampullary tumor and scheduled for laparoscopic pancreaticoduodenectomy. General anesthesia was induced at 08:05 on May 29 with endotracheal intubation utilizing sufentanil, cipepofol\u0026zwnj;, and rocuronium. Mechanical ventilation was initiated with 100% oxygen in pressure‒volume control mode, targeting a tidal volume of 7 ml/kg. Standard noninvasive monitoring and invasive arterial blood pressure monitoring methods were established. A serum potassium level measured at 08:50 revealed critical hypokalemia (2.71 mmol/L). Consequently, 2 g (26.8 mEq) of potassium chloride was administered intravenously via a central venous line over 6 hours. Remifentanil, cipepofol, sevoflurane and rocuronium were used for intraoperative anesthesia maintenance.\u003c/p\u003e\u003cp\u003eThe patient underwent a laparoscopic Whipple procedure with resection of the pancreatic head, duodenum, distal stomach, common bile duct, and gallbladder. Intraoperative blood loss was minimal (100 mL). During the 6-hour 40-minute procedure (10:20), the serum potassium level measured at 16:41 was 3.28 mmol/L. The procedure ended at 17:00. After tracheal extubation at 17:25 in the postanesthesia care unit (PACU), the patient remained stable and was transferred to the ward at 17:50. At 18:19, the patient acutely developed hypertension, tachycardia, and new-onset arrhythmias. The rapid decline in potassium levels directly precipitated refractory ventricular arrhythmias and cardiac arrest. Cardiac arrest occurred at 18:35, prompting immediate CPR with intravenous epinephrine. Intensive care physicians performed endotracheal intubation and manual ventilation. Defibrillator monitoring revealed PEA, a nonshockable rhythm. Following continued CPR, spontaneous circulation returned at 18:58, with sinus tachycardia (150\u0026ndash;170 bpm), hypertension (167/121 mmHg), and a peripheral oxygen saturation of 98%. Bilateral pupillary dilation (5.5 mm) with an absent light reflex was noted. The patient was transferred to the ICU for mechanical ventilation and hemodynamic support.\u003c/p\u003e\u003cp\u003eComprehensive ICU care included potassium repletion, mechanical ventilation, neuroprotection (hypothermia, osmotherapy), hemodynamic support (vasodilators, vasopressors, inotropes), infection control (antibiotics), organ-specific therapies (corticosteroids, cardioprotectives, neurotrophic factors, renal preservation), nutrition, and homeostasis maintenance. Subsequent delays in identifying and correcting concurrent hypocalcemia likely compounded myocardial injury. The changes in the serum potassium and ionized calcium levels on the day of cardiac arrest and after surgery are shown in Fig.\u0026nbsp;1A-B. The patient underwent neurosurgical intervention, with a subsequent diagnosis of HIE complicated by concurrent cardiac, hepatic, and renal dysfunction. Despite aggressive multidisciplinary management (involving cardiology, neurosurgery, and the intensive care unit (ICU)), the patient failed to regain full consciousness and progressed to deep coma. Sulcal effacement in the frontal regions, consistent with cerebral edema, was observed via cranial computed tomography (CT) (Fig.\u0026nbsp;1C).\u003c/p\u003e\u003cp\u003e\u003cb\u003eFigure 1. Serum electrolyte dynamics and evolution of brain edema following cardiac arrest.\u003c/b\u003e\u003c/p\u003e\u003cp\u003e(A) Serial serum potassium and calcium levels postcardiac arrest. (B-C) Brain edema progression on Day 1 and Day 6 postarrest.\u003c/p\u003e\u003cp\u003eA notable aspect of this case was the presence of refractory hypokalemia, requiring substantially higher doses of potassium supplementation to maintain unstable potassium levels. A total of 33.5 g (448.9 mEq) of potassium chloride (including 2 g used in the operating room) and 34.2 g (200 mEq) of potassium aspartate injection were administered in the ICU. The changes in refractory hypokalemia from the beginning of anesthesia to death are shown in Table\u0026nbsp;1. Persistent elevation of myoglobin (MYO) and high-sensitivity cardiac troponin I (hs-cTnI) following resuscitation indicated ongoing myocardial injury and necrosis. Moreover, the sustained increase in N-terminal pro-B-type natriuretic peptide (NT-proBNP) suggested significant cardiac dysfunction and ventricular wall stress. Although initial therapeutic interventions transiently reduced biomarker levels, the subsequent rebound and refractoriness to intensified management indicated progressive myocardial damage and worsening cardiac function. The patient also presented with intermittent seizures and nonsustained ventricular tachycardia\u003csup\u003e[\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e]\u003c/sup\u003e, presented with fixed and dilated pupils (5 mm bilaterally) without light or corneal reflexes, and remained ventilator dependent. By day 14 postcardiac arrest, vital signs remained unstable (heart rate persistently\u0026thinsp;\u0026gt;\u0026thinsp;130 bpm, systolic blood pressure\u0026thinsp;\u0026lt;\u0026thinsp;90 mmHg, diastolic\u0026thinsp;\u0026lt;\u0026thinsp;60 mmHg). Following discussion, the family opted for the withdrawal of life-sustaining therapies, and the patient expired. The sequence of events and management of cardiac arrest are summarized in Fig.\u0026nbsp;\u003cspan refid=\"Fig1\" class=\"InternalRef\"\u003e2\u003c/span\u003e.\u003c/p\u003e\u003cp\u003e\u003cb\u003eTable\u0026nbsp;1. Serial cardiac markers, blood gases, and hypokalemia recovery relative to cumulative potassium supplementation from anesthetic induction until death.\u003c/b\u003e\u003c/p\u003e\u003cp\u003e\u003c/p\u003e\u003cp\u003e\u003cimg 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\"\u003e\u003c/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c/p\u003e"},{"header":"3. Discussion and conclusions","content":"\u003cp\u003eThis case illustrates fatal cardiac arrest precipitated by hypokalemia during the perioperative period. Despite aggressive resuscitation efforts, the patient succumbed to MODS, HIE, and sepsis, a cascade initiated by multifactorial pathophysiological processes, including perioperative electrolyte derangements, ischemic-reperfusion injury, and metabolic dysregulation. The primary trigger for postoperative cardiac arrest was unaddressed perioperative hypokalemia. More than two enemas throughout the body are considered risk factors for hypokalemia\u003csup\u003e[\u003cspan citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e]\u003c/sup\u003e. This rapid decline was synergistically driven by insulin-mediated transcellular potassium shifts and substantial gastrointestinal potassium losses from preoperative mechanical bowel preparation. Furthermore, dietary restriction combined with sustained insulin therapy markedly potentiated this effect.\u003c/p\u003e\u003cp\u003ePostarrest hypocalcemia exacerbates myocardial dysfunction and cerebral injury. Calcium dysregulation in cerebral ischemia‒reperfusion activates calpain-caspase apoptotic pathways, contributing to irreversible neurological injury. Exaggerated inflammatory responses, coupled with catecholamine hyperactivity, are recognized as drivers of hypocalcemia\u003csup\u003e[\u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e]\u003c/sup\u003e. While the 7-hour operative duration was within the expected limits for Whipple procedures, prolonged anesthesia and surgical trauma precipitated a systemic inflammatory response, occult hypoperfusion, insulin resistance, and stress hyperglycemia (29.4 mmol/L at the time of arrest). Hyperglycemia potentiates oxidative stress-mediated brain injury, particularly in diabetic patients\u003csup\u003e[\u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e]\u003c/sup\u003e.\u003c/p\u003e\u003cp\u003eNonetheless, we acknowledge the limitations of this report. First, regarding hypokalemia, electrolytes were not re-evaluated within 24 hours preceding the operation. Moreover, severe hypokalemia was identified intraoperatively but was not adequately corrected during the perioperative period, and delayed intervention may have contributed to arrhythmia. Second, the patient's preexisting hypertension and diabetes, although managed with medication, may have led to unrecognized microvascular dysfunction, potentially exacerbating ischemic injury following cardiac arrest\u003csup\u003e[\u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e]\u003c/sup\u003e. Hypertension requiring medication is independently associated with cardiovascular complications after Whipple procedures and may need to be considered in preoperative risk stratification\u003csup\u003e[\u003cspan citationid=\"CR9\" class=\"CitationRef\"\u003e9\u003c/span\u003e]\u003c/sup\u003e. Third, although HIE was diagnosed, advanced neurological monitoring (such as electroencephalography) was not conducted, which may have resulted in underestimation of the severity of brain damage. These limitations highlight the need for prospective studies incorporating rigorous intraoperative monitoring and standardized post arrest care pathways in high-risk surgeries.\u003c/p\u003e\u003cp\u003eIn conclusion, this case report clearly illustrates the catastrophic consequences of inadequately managed perioperative hypokalemia, particularly in insulin-treated diabetic patients undergoing major abdominal surgery, such as the Whipple procedure. This fatal event underscores critical lessons. First, high-risk patients (insulin-treated diabetic patients undergoing major surgery) require serial perioperative potassium monitoring: postbowel preparation, preoperatively on the morning of surgery, immediately upon arrival at the operating room, and intraoperatively every 60 minutes for procedures exceeding 5 hours. Proactive repletion should target a preoperative potassium\u0026thinsp;\u0026gt;\u0026thinsp;4.0 mmol/L. If necessary, surgery should be postponed until the internal environment is optimized. Second, therapeutic hypothermia represents one of the most widely implemented neuroprotective strategies following cardiac arrest\u003csup\u003e[\u003cspan citationid=\"CR10\" class=\"CitationRef\"\u003e10\u003c/span\u003e]\u003c/sup\u003e. The implementation of targeted temperature management (TTM) should be considered, and hyperbaric oxygen therapy may also be considered within 6 hours postarrest to mitigate HIE progression. The fatal trajectory of persistent HIE, irreversible MODS, and sepsis underscores the devastating potential of perioperative electrolyte instability in elderly patients with diminished physiological reserves. Future research must prioritize the development of validated risk stratification tools and the implementation of rigorous, protocol-driven perioperative electrolyte management strategies, especially for high-risk populations undergoing complex surgical procedures.\u003c/p\u003e"},{"header":"Abbreviations","content":"\u003cdiv class=\"DefinitionList\"\u003e\u003cdiv class=\"DefinitionListEntry\"\u003e\u003cdiv class=\"Term\"\u003ePEA\u003c/div\u003e\u003cdiv class=\"Description\"\u003e\u003cp\u003epulseless electrical activity\u003c/p\u003e\u003c/div\u003e\u003c/div\u003e\u003cdiv class=\"DefinitionListEntry\"\u003e\u003cdiv class=\"Term\"\u003eCPR\u003c/div\u003e\u003cdiv class=\"Description\"\u003e\u003cp\u003ecardiopulmonary resuscitation\u003c/p\u003e\u003c/div\u003e\u003c/div\u003e\u003cdiv class=\"DefinitionListEntry\"\u003e\u003cdiv class=\"Term\"\u003eICU\u003c/div\u003e\u003cdiv class=\"Description\"\u003e\u003cp\u003eintensive care unit\u003c/p\u003e\u003c/div\u003e\u003c/div\u003e\u003cdiv class=\"DefinitionListEntry\"\u003e\u003cdiv class=\"Term\"\u003eHIE\u003c/div\u003e\u003cdiv class=\"Description\"\u003e\u003cp\u003ehypoxic-ischemic encephalopathy\u003c/p\u003e\u003c/div\u003e\u003c/div\u003e\u003cdiv class=\"DefinitionListEntry\"\u003e\u003cdiv class=\"Term\"\u003eMODS\u003c/div\u003e\u003cdiv class=\"Description\"\u003e\u003cp\u003emultiple organ disfunction\u003c/p\u003e\u003c/div\u003e\u003c/div\u003e\u003cdiv class=\"DefinitionListEntry\"\u003e\u003cdiv class=\"Term\"\u003ePACU\u003c/div\u003e\u003cdiv class=\"Description\"\u003e\u003cp\u003epostanesthesia care unit\u003c/p\u003e\u003c/div\u003e\u003c/div\u003e\u003cdiv class=\"DefinitionListEntry\"\u003e\u003cdiv class=\"Term\"\u003eCT\u003c/div\u003e\u003cdiv class=\"Description\"\u003e\u003cp\u003ecomputed tomography\u003c/p\u003e\u003c/div\u003e\u003c/div\u003e\u003cdiv class=\"DefinitionListEntry\"\u003e\u003cdiv class=\"Term\"\u003eMYO\u003c/div\u003e\u003cdiv class=\"Description\"\u003e\u003cp\u003emyoglobin\u003c/p\u003e\u003c/div\u003e\u003c/div\u003e\u003cdiv class=\"DefinitionListEntry\"\u003e\u003cdiv class=\"Term\"\u003ehs-cTnI\u003c/div\u003e\u003cdiv class=\"Description\"\u003e\u003cp\u003ehigh-sensitivity cardiac troponin I\u003c/p\u003e\u003c/div\u003e\u003c/div\u003e\u003cdiv class=\"DefinitionListEntry\"\u003e\u003cdiv class=\"Term\"\u003eNT-proBNP\u003c/div\u003e\u003cdiv class=\"Description\"\u003e\u003cp\u003eN-terminal pro-B-type natriuretic peptide\u003c/p\u003e\u003c/div\u003e\u003c/div\u003e\u003cdiv class=\"DefinitionListEntry\"\u003e\u003cdiv class=\"Term\"\u003eTTM\u003c/div\u003e\u003cdiv class=\"Description\"\u003e\u003cp\u003etargeted temperature management\u003c/p\u003e\u003c/div\u003e\u003c/div\u003e\u003c/div\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003eEthics approval and consent to participate\u003c/strong\u003e\u003cp\u003eEthical approval for this case report was officially waived by the Medical Ethics Committee of Guangzhou Medical University Cancer Center. This waiver is consistent with institutional policies and international guidelines for retrospective analysis of anonymized single-patient cases intended for educational purposes. The written informed consent form discloses anonymous medical details from the legally authorized representative of the patient's family. All procedures adhered to the principles of the Declaration of Helsinki.\u003c/p\u003e\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eConsent for publication\u003c/strong\u003e\u003cp\u003e Written informed consent was obtained from the patient for publication of this case report and the accompanying data.\u003c/p\u003e\u003c/p\u003e\u003cp\u003e\u003ch2\u003eCompeting interests\u003c/h2\u003e\u003cp\u003eThe authors declare that they have no competing interests.\u003c/p\u003e\u003c/p\u003e\u003ch2\u003eFunding\u003c/h2\u003e\u003cp\u003eNot applicable.\u003c/p\u003e\u003ch2\u003eAuthor Contribution\u003c/h2\u003e\u003cp\u003eWH and CG wrote the main manuscript text and prepared the figures and table. RZ contributed to manuscript revisions and supervision of the manuscript. All authors reviewed the manuscript.\u003c/p\u003e\u003ch2\u003eAcknowledgments\u003c/h2\u003e\u003cp\u003eNot applicable.\u003c/p\u003e\u003ch2\u003eAvailability of data and materials\u003c/h2\u003e\u003cp\u003eThe data generated and analyzed during the current case are not publicly available to protect patient privacy, but they are available from the corresponding author upon reasonable request.\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\u003cli\u003e\u003cspan\u003eSmith EB, Hardart R. Pancreaticoduodenectomy (Whipple Procedure) in a Toddler: An Anesthesia Case Report. A A Pract. 2019. 13(8): 303\u0026ndash;5.\u003c/span\u003e\u003c/li\u003e\u003cli\u003e\u003cspan\u003eHakakian D, Bellaire AJ, Elsawwah JK, Harrison LE, Rolandelli RH, Nemeth ZH. Risk Factors and Surgical Outcomes of Older Adult Patients Undergoing a Whipple Procedure. South Med J. 2025;118(3):184\u0026ndash;8.\u003c/span\u003e\u003c/li\u003e\u003cli\u003e\u003cspan\u003eCasey B 3rd, Hofstrand R, Patel D, Bahekar A, Chapa-Rodriguez A. Hypokalemia-Induced Cardiac Arrest Cureus. 2023;15(2):e35034.\u003c/span\u003e\u003c/li\u003e\u003cli\u003e\u003cspan\u003eBhellum P, Angirekula S, Kumar Rohila A, Sharma A, Gupta A, Mathur N. Novel TRPM3 missense mutation leading to severe hypocalcemia presenting as seizures and complicated by non-sustained ventricular tachycardia: A case report. Qatar Med J. 2025;2025(1):28.\u003c/span\u003e\u003c/li\u003e\u003cli\u003e\u003cspan\u003eWang BB, Hu L, Hu XY, Han D, Wu J. Risk Factors Asscociated with Hypokalemia during Postanesthesia Recovery and Its Impact on Outcomes in Gynecological Patients: A Propensity Score Matching Study. Curr Med Sci. 2024;44(2):441\u0026ndash;9.\u003c/span\u003e\u003c/li\u003e\u003cli\u003e\u003cspan\u003eMelchers M, Moonen H, Breeman TM, van Bree S, van Zanten A. Parenteral calcium administration and outcomes in critically ill patients with hypocalcemia: A retrospective cohort study. J Intensive Med. 2025;5(2):151\u0026ndash;9.\u003c/span\u003e\u003c/li\u003e\u003cli\u003e\u003cspan\u003eLong C, Pu Y, Keng S, Tao J, Zhang B, Yue R. Novel Insights into the Mechanism and Treatment of Diabetes-Related Brain Complications: Focusing on the Blood-Brain Barrier Impairment. Aging Dis. 2025.\u003c/span\u003e\u003c/li\u003e\u003cli\u003e\u003cspan\u003eGazivoda VP, Greenbaum A, Beier MA, et al. Pancreatoduodenectomy: the Metabolic Syndrome is Associated with Preventable Morbidity and Mortality. J Gastrointest Surg. 2022;26(10):2167\u0026ndash;75.\u003c/span\u003e\u003c/li\u003e\u003cli\u003e\u003cspan\u003eLin JJ, Conroy PC, Romero-Hernandez F, et al. Hypertension Requiring Medication Use: a Silent Predictor of Poor Outcomes After Pancreaticoduodenectomy. J Gastrointest Surg. 2023;27(2):328\u0026ndash;36.\u003c/span\u003e\u003c/li\u003e\u003cli\u003e\u003cspan\u003ePerkins GD, Neumar R, Hsu CH et al. Improving Outcomes After Post-Cardiac Arrest Brain Injury: A Scientific Statement from the International Liaison Committee on Resuscitation. Circulation. 2024.\u003c/span\u003e\u003c/li\u003e\u003c/ol\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"bmc-anesthesiology","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"bane","sideBox":"Learn more about [BMC Anesthesiology](http://bmcanesthesiol.biomedcentral.com/)","snPcode":"","submissionUrl":"https://www.editorialmanager.com/bane","title":"BMC Anesthesiology","twitterHandle":"BMC_series","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"em","reportingPortfolio":"BMC Series","inReviewEnabled":true,"inReviewRevisionsEnabled":true},"keywords":"Perioperative, Anesthesia, Cardiac arrest, Hypokalemia, Whipple procedure, Hypoxic-ischemic encephalopathy (HIE), Multiple organ dysfunction (MODS)","lastPublishedDoi":"10.21203/rs.3.rs-7184221/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-7184221/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground:\u003c/strong\u003e Pancreaticoduodenectomy(Whipple procedure) isa highly complex abdominal surgical procedure, and while perioperative cardiac arrest is infrequent, it is associated with significant morbidity. The established risk factors for postoperative cardiac arrest includehypovolemia, acidosis, and electrolyte imbalances.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCase presentation: \u003c/strong\u003eWe present the case of a 67-year-old female with a history of type 1 diabetes mellitus and hypertension who underwent a Whipple procedure under general anesthesia. Preoperative serum potassium levels, which were measured three days prior, were within normal limits (5.28 mmol/L). However, profound hypokalemia (2.71 mmol/L) was detected before the skin incision, and the anesthesiologisttreated the patient with 2 g (26.8 mEq) of intravenous potassium chloride under cardiac output monitoring. The posttreatment serum potassium level at 16:41 was 3.28 mmol/L, indicating persistent hypokalemia. Following the procedure, the patient's vital signs stabilized, meeting the criteria for transfer to the general ward. However, within 30 minutes of ward arrival, the patient experienced a sudden episode of hypertension and tachycardia, rapidly progressing to pulseless electrical activity (PEA) cardiac arrest. Immediate resuscitation efforts, including continuous cardiopulmonary resuscitation (CPR) and epinephrine administration, were initiated. After spontaneous circulation returned, the patient was transferred to the intensive care unit (ICU) and subsequently diagnosed with hypoxic-ischemicencephalopathy (HIE), multiple organ dysfunction syndrome (MODS), or sepsis. Ultimately, the patient succumbed to these complications on day 14 of ICU admission.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusions: \u003c/strong\u003eThis critical event underscores the vital importance of meticulous perioperative potassium management in diabetic patients undergoing major abdominal surgery. We advocate for mandatory reevaluation of electrolyte levels within 24 hours preoperatively, particularly following bowel preparation and dietary restriction, in conjunction with prophylactic potassium supplementation and careful insulin administration, as crucial measures to prevent such devastating outcomes.\u003c/p\u003e","manuscriptTitle":"The Silent Potassium Avalanche: Unchecking Preoperative Hypokalemia Leading to Perioperative Cardiac Arrest in an Insulin-Treated Diabetic Patient Undergoing a Whipple Procedure: A Case Report","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-08-08 16:18:23","doi":"10.21203/rs.3.rs-7184221/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Revision requested","date":"2025-09-10T12:48:26+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-09-07T14:16:08+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"326742018992121888664256375499788681621","date":"2025-09-07T13:53:07+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"209831823005664089591740707415436753799","date":"2025-09-05T13:35:44+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-08-22T12:45:11+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-08-15T18:52:49+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"209439363118507010141313362555667305044","date":"2025-08-12T13:04:35+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"264466651597322503447169609069255831318","date":"2025-08-12T11:14:32+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"56713810706560499550136394405904761786","date":"2025-08-12T07:53:46+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2025-08-05T04:53:35+00:00","index":"","fulltext":""},{"type":"editorInvited","content":"","date":"2025-08-04T13:42:38+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2025-07-30T06:50:17+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2025-07-30T06:49:14+00:00","index":"","fulltext":""},{"type":"submitted","content":"BMC Anesthesiology","date":"2025-07-22T07:58:02+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"bmc-anesthesiology","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"bane","sideBox":"Learn more about [BMC Anesthesiology](http://bmcanesthesiol.biomedcentral.com/)","snPcode":"","submissionUrl":"https://www.editorialmanager.com/bane","title":"BMC Anesthesiology","twitterHandle":"BMC_series","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"em","reportingPortfolio":"BMC Series","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"264d4374-0aa9-435e-9f08-8692b098bcf7","owner":[],"postedDate":"August 8th, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[],"tags":[],"updatedAt":"2025-12-01T16:08:41+00:00","versionOfRecord":{"articleIdentity":"rs-7184221","link":"https://doi.org/10.1186/s12871-025-03481-5","journal":{"identity":"bmc-anesthesiology","isVorOnly":false,"title":"BMC Anesthesiology"},"publishedOn":"2025-11-28 15:58:36","publishedOnDateReadable":"November 28th, 2025"},"versionCreatedAt":"2025-08-08 16:18:23","video":"","vorDoi":"10.1186/s12871-025-03481-5","vorDoiUrl":"https://doi.org/10.1186/s12871-025-03481-5","workflowStages":[]},"version":"v1","identity":"rs-7184221","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-7184221","identity":"rs-7184221","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}