Clinicopathologic characteristics of 3 malignant transforming of adenomyosis

Objective:To investigate the clinicopathologic characteristics of malignant transforming of adenomyosis.Methods: A retrospective analysis was performed on 3 cases that diagnosed in our hospital during January 2001-December 2010.Results: The age of 3 patients were 45,56 and 58 years.The most common presenting symptoms were hypermenorrhea,menstruation,postmenopausal bleeding and deep dyspareunia.Serum CA125 levels were 34.98 U/ml,196.6 U/ml and 22.4 U/ml,and ultrasound were not specific.Only pathology can make up the diognosis.The treatment method was operation plus irradiation,or operation plus chemotherapy.Conclusion: Malignant transformation of adenomyosis is not exceptional disease,preoperative diagnosis is difficult,easer for misdiagnose.We should improve our knowledge for its early diagnosis,good intervention.