Synthetic Controls with Multiple Outcomes: Estimating the Effects of Non-Pharmaceutical Interventions in the COVID-19 Pandemic

We propose a generalization of the synthetic control method to a multiple-outcome framework, which improves the reliability of treatment effect estimation. This is done by supplementing the conventional pre-treatment time dimension with the extra dimension of related outcomes in computing the synthetic control weights. Our generalization can be particularly useful for studies evaluating the effect of a treatment on multiple outcome variables. To illustrate our method, we estimate the effects of non-pharmaceutical interventions (NPIs) on various outcomes in Sweden in the first 3 quarters of 2020. Our results suggest that if Sweden had implemented stricter NPIs like the other European countries by March, then there would have been about 70% fewer cumulative COVID-19 infection cases and deaths by July, and 20% fewer deaths from all causes in early May, whereas the impacts of the NPIs were relatively mild on the labor market and economic outcomes.