RadarOmics: Intuitive visualisation of multidimensional omics data in ecological, evolutionary, and developmental studies

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This paper describes RadarOmics, an R package for intuitive visualization of multidimensional omics data, designed to better capture coordinated, system-level patterns across multiple biological processes than traditional heatmaps or enrichment plots. The authors implement dimensional reduction methods (scaling, PCA, or LDA) to generate representative values for predefined processes per sample, then display these values using multi-axis circular radar plots to highlight global trends, outliers, and trade-offs. Using transcriptomic datasets from anemonefish metamorphosis and zebrafish chemical exposure assays, they report that radar-based visualizations reveal coordinated molecular responses that are less readily apparent with conventional visual outputs. The paper does not state any explicit limitation of the approach beyond focusing on visualization and process summarization, and it does not evaluate clinical or disease-specific cohorts. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Interpreting high-dimensional omics datasets requires visualisation tools that reveal coordinated responses across multiple biological processes. Existing approaches such as heatmaps or enrichment plots typically present processes independently and struggle to convey system-level patterns as experimental complexity increases. We developed RadarOmics, an R package that integrates multidimensional omics data using multi-axis radar visualisations. RadarOmics performs dimensional reduction (based on scaling, Principal Component Analyses, or Linear Discriminant Analyses) for predefined biological processes to extract a representative value for each sample and process of interest. These values are displayed in a circular radar layout, enabling rapid identification of global trends, outliers, and trade-offs among biological functions. Using transcriptomic datasets from anemonefish metamorphosis and zebrafish chemical exposure assays, we show that radar-based visualisations can reveal coordinated molecular responses that are less readily captured with traditional visualisation outputs. RadarOmics provides a flexible and intuitive framework for summarising and interpreting biological variation in ecological, evolutionary, and developmental omics studies, offering a compact system-level overview of molecular behaviour across complex experimental designs.
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Abstract Interpreting high-dimensional omics datasets requires visualisation tools that reveal coordinated responses across multiple biological processes. Existing approaches such as heatmaps or enrichment plots typically present processes independently and struggle to convey system-level patterns as experimental complexity increases. We developed RadarOmics, an R package that integrates multidimensional omics data using multi-axis radar visualisations. RadarOmics performs dimensional reduction (based on scaling, Principal Component Analyses, or Linear Discriminant Analyses) for predefined biological processes to extract a representative value for each sample and process of interest. These values are displayed in a circular radar layout, enabling rapid identification of global trends, outliers, and trade-offs among biological functions. Using transcriptomic datasets from anemonefish metamorphosis and zebrafish chemical exposure assays, we show that radar-based visualisations can reveal coordinated molecular responses that are less readily captured with traditional visualisation outputs. RadarOmics provides a flexible and intuitive framework for summarising and interpreting biological variation in ecological, evolutionary, and developmental omics studies, offering a compact system-level overview of molecular behaviour across complex experimental designs. Competing Interest Statement The authors have declared no competing interest.

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last seen: 2026-05-20T01:45:00.602351+00:00