COMPOSITIONS AND METHODS FOR TREATING PROGESTERONE-DEPENDENT CONDITIONS
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The invention discloses compositions and methods using 19-norsteroid progesterone receptor modulators with low antiglucocorticoid activity to treat endometriosis, dysmenorrhea, breast cancer, uterine fibroids, and endometrial hyperproliferation.
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Abstract
The subject matter of the instant invention is pertinent to the field of treatment of progesterone-dependent conditions. Compositions for practicing the methods, comprising one or more 19-norsteroid progesterone receptor modulators having a monomethylamine-substituted phenyl ring at the 11 ss-position of carbon 11 and exhibiting low antiglucocorticoid activity, are also disclosed. Embodiments of the instant invention disclose methods for treating endometriosis, dysmenorrhea, breast cancer, uterine fibroids and endometrial hyperproliferation.
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- europepmc
- last seen: 2026-10-10T06:11:15.153948+00:00