Anatomic Causes for Delayed Puberty
This review systematically examines anatomic causes for delayed puberty in females, detailing embryology, diagnosis, treatment, and potential fertility options for various congenital abnormalities.
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This paper is a systematic review/chapter describing anatomic abnormalities in females that can cause absent menses and delayed puberty, outlining embryologic basis, diagnostic considerations, and management approaches. It reports that anatomic causes have an incidence of 23.7% and states that some abnormalities can be addressed surgically to restore menstrual function, while others involve congenital absence of uterine or vaginal structures and cannot restore outflow tract connections. For cases where restoration is not possible, the chapter describes medical and surgical options aimed at minimizing pain, reducing the risk of endometriosis, and creating a functional vaginal space. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.
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Cites (4)
- Expression of HOXA11 in the mid-luteal endometrium from women with endometriosis-associated infertility 2012
- Reproductive performance of women with müllerian anomalies 2007
- Transforming Growth Factor β Receptor Type 1 Is Essential for Female Reproductive Tract Integrity and Function 2011
- Imaging diagnosis of congenital uterine malformation 2004
References (29)
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