[Retracted] MicroRNA‑202 inhibits endometrial stromal cell migration and invasion by suppressing the K‑Ras/Raf1/MEK/ERK signaling pathway

Di Zhang, Zhang D, Wang L, Ling Wang, Hua-Lei Guo, Guo HL, Zi-Wei Zhang, Zhang ZW, Wang C, Chong Wang, Chian RC, Ri-Cheng Chian, Zhang ZF, Zhi-Fen Zhang
International journal of molecular medicine · 2024 · vol. 53(6) · doi:10.3892/ijmm.2024.5375 · PMID:38606498 · PMC11090261
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This paper on microRNA-202 inhibiting endometrial stromal cell migration in endometriosis was retracted due to data similarity with another publication and lack of satisfactory explanation from the authors.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-14 · read from full text ⓘ

This retracted article originally claimed that microRNA-202 inhibits the migration and invasion of endometrial stromal cells by suppressing the K-Ras/Raf1/MEK/ERK signaling pathway. The publication was withdrawn after a reader alerted the editor that specific Transwell invasion assay data were strikingly similar to data from a different study submitted for publication elsewhere. The authors failed to provide a satisfactory explanation for these concerns, leading the editorial office to decide on retraction due to potential scientific misconduct. Relevance to endometriosis: listed as one indication for GnRH antagonists, though the paper's main focus is uterine fibroids.

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Abstract

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell invasion assay data shown in Figs. 2C and 4B were strikingly similar to data appearing in different form in a paper by different authors at a different research institute that had already been submitted for publication. Owing to the fact that the contentious data in the above article had already been submitted for publication prior to its submission to International Journal of Molecular Medicine, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused. [International Journal of Molecular Medicine 46: 2078‑2088, 2020; DOI: 10.3892/ijmm.2020.4749].
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Print ISSN: 1107-3756 Online ISSN: 1791-244X International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease. International Journal of Oncology is an international journal devoted to oncology research and cancer treatment. Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery. Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine. Oncology Letters is an international journal devoted to Experimental and Clinical Oncology. Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology. International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis. Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology. Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition. Publishes open-access research on using epigenetics to advance understanding and treatment of human disease. An International Open Access Journal Devoted to General Medicine. Retraction Open Access - Authors: - Article Number: 51|Published online on: April 8, 2024https://doi.org/10.3892/ijmm.2024.5375 - Expand metrics + Int J Mol Med 46: [Related article:] 2078-2088, 2020; DOI: 10.3892/ijmm.2020.4749 Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell invasion assay data shown in Figs. 2C and 4B were strikingly similar to data appearing in different form in a paper by different authors at a different research institute that had already been submitted for publication. Owing to the fact that the contentious data in the above article had already been submitted for publication prior to its submission to International Journal of Molecular Medicine, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused. Copy and paste a formatted citation Spandidos Publications style Zhang D, Wang L, Guo H, Zhang Z, Wang C, Chian R and Zhang Z: [Retracted] MicroRNA‑202 inhibits endometrial stromal cell migration and invasion by suppressing the K‑Ras/Raf1/MEK/ERK signaling pathway. Int J Mol Med 53: 51, 2024. APA Zhang, D., Wang, L., Guo, H., Zhang, Z., Wang, C., Chian, R., & Zhang, Z. (2024). [Retracted] MicroRNA‑202 inhibits endometrial stromal cell migration and invasion by suppressing the K‑Ras/Raf1/MEK/ERK signaling pathway. International Journal of Molecular Medicine, 53, 51. https://doi.org/10.3892/ijmm.2024.5375 MLA Zhang, D., Wang, L., Guo, H., Zhang, Z., Wang, C., Chian, R., Zhang, Z."[Retracted] MicroRNA‑202 inhibits endometrial stromal cell migration and invasion by suppressing the K‑Ras/Raf1/MEK/ERK signaling pathway". International Journal of Molecular Medicine 53.6 (2024): 51. Chicago Zhang, D., Wang, L., Guo, H., Zhang, Z., Wang, C., Chian, R., Zhang, Z."[Retracted] MicroRNA‑202 inhibits endometrial stromal cell migration and invasion by suppressing the K‑Ras/Raf1/MEK/ERK signaling pathway". International Journal of Molecular Medicine 53, no. 6 (2024): 51. https://doi.org/10.3892/ijmm.2024.5375

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