Clinical study on mifepristone in treating endometriosis
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Abstract
目的探讨低剂量米非司酮治疗子宫内膜异位症的疗效.方法 22例子宫内膜异位症患者口服米非司酮12.5 mg,1次/d,连续3～6个月.比较治疗前后症状、体征及血激素水平.结果 在治疗期间所有患者均闭经,与治疗前比较,总主观症状评分于治疗3个月后下降了82.6%,6个月后下降了93.5%(P＜0.01);内膜异位症病灶于3个月后缩小了32.8%,6个月后缩小了58.2%(P＜0.01).用药3个月血孕激素水平比用药前显著降低,雌激素水平降至卵泡中期水平,黄体生成素、促卵泡激素水平均无变化.停止治疗后于24～40天恢复月经.不良反应为潮热、恶心及乏力.结论 低剂量米非司酮治疗子宫内膜异位症效果良好,副作用小,是治疗子宫内膜异位症的又一种保守治疗方法.
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- last seen: 2026-06-10T17:14:06.276822+00:00
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