Sulfonylated Heterocycles Useful for Modulation of the Progesterone Receptor
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This paper describes sulfonylated heterocycles for preparing compounds that modulate the progesterone receptor to treat endometriosis and other conditions.
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Abstract
Compounds of the following structure are provided, wherein n, R1-R3 and R6-R9 are defined below, as are methods of preparing and using these compounds for contraception treating or preventing fibroids, uterine leiomyomata, endometriosis, dysfunctional bleeding, polycystic ovary syndrome, and hormone-dependent carcinomas providing hormone replacement therapy stimulating food intake synchronizing estrus and treating cycle-related symptoms.
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- europepmc
- last seen: 2026-10-12T06:17:10.165071+00:00