Agonists of gonadotropin-releasing hormone: their role in the complex therapy of hyperplastic processes in reproductive organs

Л. В. Ткаченко, Nataliya Ivanovna Sviridova
In: Journal of obstetrics and women's diseases · 2014 · vol. 63(2) , pp. 6–11 · doi:10.17816/jowd6326-11 · W2340786077
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This study evaluated Buserilin efficacy in 108 patients aged 41-52 with endometriosis and concurrent endometrial hyperplasia, finding that postoperative GnRH agonist therapy followed by progestogens or oral contraceptives effectively prevents relapse.

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The provided text does not contain the abstract or body of the research paper titled "Agonists of gonadotropin-releasing hormone: their role in the complex therapy of hyperplastic processes in reproductive organs." Instead, it consists of website subscription prompts and legal disclaimers regarding personal data processing and media registration with Roskomnadzor. Consequently, no study population, methods, or findings can be extracted from the available content. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

The aim of this study was to evaluate the efficacy of an agonist of gonadotropin-releasing hormone Buserilin in the treatment of patients with endometriosis in combination with endometrial hyperplasia. We conducted a clinical and laboratory examination and treatment of 108 patients aged 41 to 52 years old suffering from endometriosis varying degrees of prevalence in conjunction with endometrial hyperplasia. The results obtained suggest a scientifically sound complex treatment of patients with endometriosis on the background of endometrial hyperplasia with a GnRH agonist Buserilin-depo in the postoperative period, followed by the appointment of progestogens or combiened oral contraceptives as a long-term program management of patients to prevent relapse and re-operative treatment.
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endometriosis

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