Initial experience using a novel cryoballoon with variable balloon sizing - The ICE AGE FIT study -

Initial experience using a novel cryoballoon with variable balloon sizing - The ICE AGE FIT study - | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 17 April 2025 V1 Latest version Share on Initial experience using a novel cryoballoon with variable balloon sizing - The ICE AGE FIT study - Authors : Behnam Subin [email protected] , Christian-Hendrik Heeeger 0000-0002-9014-8097 , Merwan Wahab , Patrick Badertscher 0000-0001-9751-0557 , Corinne Isenegger 0009-0001-9623-3997 , Philipp Buhs , Sascha Hatahet 0000-0002-3061-2249 , Jan-Per Wenzel , Charlotte Eitel , Karl-Heinz Kuck , and Roland Tilz Authors Info & Affiliations https://doi.org/10.22541/au.174490074.47241808/v1 254 views 168 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Background: A novel Cryoballoon (n-CB) system offers new and unique features to potentially improve safety, feasibility and efficacy as well as 12-month clinical outcome of CB based pulmonary vein isolation (PVI). In particular, the variable sizing of the novel CB (n-CB) ranging from 28 to 31 mm aims to fit different pulmonary vein (PV) anatomies as well as a more stable balloon positioning. The aim of this study was to assess the safety, feasibility and efficacy as well as 12-month clinical outcome of the n-CB system compared to the conventional CB (c-CB) without a variable diameter. Methods and results: We included 104 patients receiving CB-based PVI using the n-CB. The control groups consisted of 52 patients undergoing the procedure using the c-CB (n = 52). The two groups were analysed in terms of baseline and procedural data as well as 1 year follow up. A total of 104 consecutive patients with paroxysmal (n=43) and persistent (n=61) atrial fibrillation were analyzed. The mean age was 66.2 ± 11.5 years (n-CB) and 67.4 ± 11.6 (c-CB). A total of 208 (n-CB) and 205 (c-CB) PV were identified. Acute PVI was achieved in all patients in both groups. The median procedure time was 54.1 ± 18.8 min in the n-CB group and 53.6 ± 11.9 in the c-CB group (p=0.708). No differences in mean fluoroscopy time and severe adverse events were observed. No statistical differences were observed regarding the 12-month follow up between the groups. Conclusion: The n-CB showed similar safety, efficacy and a 12-months recurrence-free survival compared to the c-CB. Significantly shorter fluoroscopy duration and lower fluoroscopy dose was observed int the n-CB group. Although lower nadir balloon temperatures were noted in the c-CB group, lower esophageal temperatures at the left-sided PVs were observed in the n-CB group. Supplementary Material File (ice age fit study.docx) Download 326.74 KB Information & Authors Information Version history V1 Version 1 17 April 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords basic: atrial fibrillation/atrial arrhythmias clinical: cardiac anatomy clinical: catheter ablation – atrial fibrillation clinical: electrophysiology – autonomic nervous system clinical: epidemiology/clinical trials Authors Affiliations Behnam Subin [email protected] Universitatsklinikum Schleswig-Holstein Universitares Herzzentrum Lubeck View all articles by this author Christian-Hendrik Heeeger 0000-0002-9014-8097 Universitatsklinikum Schleswig-Holstein Universitares Herzzentrum Lubeck View all articles by this author Merwan Wahab Universitatsklinikum Schleswig-Holstein Universitares Herzzentrum Lubeck View all articles by this author Patrick Badertscher 0000-0001-9751-0557 Universitatsspital Basel Kardiologie View all articles by this author Corinne Isenegger 0009-0001-9623-3997 Universitatsspital Basel Kardiologie View all articles by this author Philipp Buhs Universitatsklinikum Schleswig-Holstein Universitares Herzzentrum Lubeck View all articles by this author Sascha Hatahet 0000-0002-3061-2249 Universitatsklinikum Schleswig-Holstein Universitares Herzzentrum Lubeck View all articles by this author Jan-Per Wenzel Universitatsklinikum Schleswig-Holstein Universitares Herzzentrum Lubeck View all articles by this author Charlotte Eitel Universitatsklinikum Schleswig-Holstein Universitares Herzzentrum Lubeck View all articles by this author Karl-Heinz Kuck Universitatsklinikum Schleswig-Holstein Universitares Herzzentrum Lubeck View all articles by this author Roland Tilz Universitatsklinikum Schleswig-Holstein Universitares Herzzentrum Lubeck View all articles by this author Metrics & Citations Metrics Article Usage 254 views 168 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Behnam Subin, Christian-Hendrik Heeeger, Merwan Wahab, et al. Initial experience using a novel cryoballoon with variable balloon sizing - The ICE AGE FIT study -. Authorea . 17 April 2025. DOI: https://doi.org/10.22541/au.174490074.47241808/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . Format Please select one from the list RIS (ProCite, Reference Manager) EndNote BibTex Medlars RefWorks Direct import Tips for downloading citations document.getElementById('citMgrHelpLink').addEventListener('click', function() { popupHelp(this.href); return false; }); $(".js__slcInclude").on("change", function(e){ if ($(this).val() == 'refworks') $('#direct').prop("checked", false); $('#direct').prop("disabled", ($(this).val() == 'refworks')); }); View Options View options PDF View PDF Figures Tables Media Share Share Share article link Copy Link Copied! Copying failed. Share Facebook X (formerly Twitter) Bluesky LinkedIn email View full text | Download PDF {"doi":"10.22541/au.174490074.47241808/v1","type":"Article"} Now Reading: Share Figures Tables Close figure viewer Back to article Figure title goes here Change zoom level Go to figure location within the article Download figure Toggle share panel Toggle share panel Share Toggle information panel Toggle information panel Go to previous graphic Go to next graphic Go to previous table Go to next table All figures All tables View all material View all material xrefBack.goTo xrefBack.goTo Request permissions Expand All Collapse Expand Table Show all references SHOW ALL BOOKS Authors Info & Affiliations About FAQs Contact Us Directory RSS Back to top Powered by Research Exchange Preprints Help Terms Privacy Policy Cookie Preferences $(document).ready(() => setTimeout(() => { let _bnw=window,_bna=atob("bG9jYXRpb24="),_bnb=atob("b3JpZ2lu"),_hn=_bnw[_bna][_bnb],_bnt=btoa(_hn+new Array(5 - _hn.length % 4).join(" ")); $.get("/resource/lodash?t="+_bnt); },4000)); (function(){function c(){var b=a.contentDocument||a.contentWindow.document;if(b){var d=b.createElement('script');d.innerHTML="window.__CF$cv$params={r:'9ff0ff15bb6f41e2',t:'MTc3OTMzOTQwNQ=='};var a=document.createElement('script');a.src='/cdn-cgi/challenge-platform/scripts/jsd/main.js';document.getElementsByTagName('head')[0].appendChild(a);";b.getElementsByTagName('head')[0].appendChild(d)}}if(document.body){var a=document.createElement('iframe');a.height=1;a.width=1;a.style.position='absolute';a.style.top=0;a.style.left=0;a.style.border='none';a.style.visibility='hidden';document.body.appendChild(a);if('loading'!==document.readyState)c();else if(window.addEventListener)document.addEventListener('DOMContentLoaded',c);else{var e=document.onreadystatechange||function(){};document.onreadystatechange=function(b){e(b);'loading'!==document.readyState&&(document.onreadystatechange=e,c())}}}})();