Роль оксидативного стресу в генезі ендометріозу

A comparison of frequencies of allelic variants of genes GSTM1, GSTT1, CYP2D6 in women with endometriosis (139 women) and healthy women (192 women in the control group) was made, and the state of lipid peroxidation in women studied groups was study. The results showed that activity of lipid peroxidation higher in women with endometriosis, regardless of the site of endometriotic lesions, compared with the control group of healthy women. This demonstrates the importance of oxidative stress in the endometriosis formation. Also, the results of research suggest that one way of leveling oxidative stress in women with endometriosis can be used of ferric drugs (Maltofer), due to the peculiarities of their digestion and minimize the risk of oxidative stress worsening.