Prevalence and Severity of Endometriosis at Laparoscopic Treatment of Tubal Ectopic Pregnancy

Jennifer Dean, Stephen Lee, Lee S, Charlotte Reddington, Reddington C, Claudia Cheng, Cheng C, Michal Amir, Amir M, Martin Healey, Healey M
The Australian & New Zealand journal of obstetrics & gynaecology · 2026 · vol. 66(1) , pp. e70050 · doi:10.1111/ajo.70050 · PMID:40433820
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-10 ⓘ

This study found endometriosis in 55% of women undergoing laparoscopic treatment for tubal ectopic pregnancy, with most cases being minimal or mild, and little correlation between patient symptoms and disease severity.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text ⓘ

This prospective observational cohort study examined the prevalence and r-ASRM stage of endometriosis in 65 women undergoing laparoscopic treatment for histologically confirmed tubal ectopic pregnancy at a tertiary hospital. Using a pre-operative patient questionnaire and a post-operative surgical assessment of endometriosis presence and severity, the authors found laparoscopically confirmed endometriosis in 36 of 65 participants, for a prevalence of 55%, with r-ASRM stage I–II accounting for 92% of cases. The study reported little correlation between the severity of reported endometriosis symptoms and the laparoscopic staging, with the main caveat being that symptom–stage comparison may be limited by the study’s design and assessments. This paper is centrally about endometriosis — it quantifies endometriosis prevalence and severity at the time of laparoscopic management of tubal ectopic pregnancy.

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Abstract

BACKGROUND: Endometriosis may have a causal role in ectopic pregnancies. AIMS: To observe the prevalence and staging of endometriosis in women at the time of laparoscopic treatment of tubal ectopic pregnancy. METHODS: Prospective observational cohort study carried out in a tertiary obstetrics and gynaecology hospital. Seventy participants with ectopic pregnancy requiring laparoscopic treatment were recruited. A pre-operative questionnaire was completed by patients regarding symptoms of endometriosis and gynaecological history. A post operative questionnaire was completed by the surgical team regarding site of ectopic pregnancy, presence or absence of endometriosis and severity of endometriosis. RESULTS: After the exclusion of patients with non-tubal ectopic pregnancies, results were examined for 65 patients. Of the 65 histologically confirmed ectopic pregnancies, 36 had laparoscopically confirmed endometriosis, demonstrating a prevalence rate of 55% in our cohort. r-ARSM stage I or II (minimal or mild) disease made up 92% (33/36) of cases. There was little correlation between severity of patient symptoms and severity of endometriosis on laparoscopic evaluation. CONCLUSION: This study demonstrates endometriosis is significantly more common in women with surgically managed tubal EP compared to the general population.
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Abstract

Background Endometriosis may have a causal role in ectopic pregnancies. Aims To observe the prevalence and staging of endometriosis in women at the time of laparoscopic treatment of tubal ectopic pregnancy.

Methods

Prospective observational cohort study carried out in a tertiary obstetrics and gynaecology hospital. Seventy participants with ectopic pregnancy requiring laparoscopic treatment were recruited. A pre-operative questionnaire was completed by patients regarding symptoms of endometriosis and gynaecological history. A post operative questionnaire was completed by the surgical team regarding site of ectopic pregnancy, presence or absence of endometriosis and severity of endometriosis.

Results

After the exclusion of patients with non-tubal ectopic pregnancies, results were examined for 65 patients. Of the 65 histologically confirmed ectopic pregnancies, 36 had laparoscopically confirmed endometriosis, demonstrating a prevalence rate of 55% in our cohort. r-ARSM stage I or II (minimal or mild) disease made up 92% (33/36) of cases. There was little correlation between severity of patient symptoms and severity of endometriosis on laparoscopic evaluation.

Conclusion

This study demonstrates endometriosis is significantly more common in women with surgically managed tubal EP compared to the general population. Conflicts of Interest The authors declare no conflicts of interest.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis

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