Treatment option for infertility following failed to two cycles intrauterine insemination

ObjectiveTo explore rationalization of treatment option for infertility following failed to two cycles intrauterine insemination. Methods 211 patients following failed to two cycles intrauterine insemination from 2001 to 2009 were analyzedretrospectively. The patients were divided into 4 groups according treatment option for infertility:medicament group,IUI group,IVF group,laparoscope group. The pathogeny of infertility,age,the rate of clinical pregnancy were compared among the groups. Results The patients in laparoscope group were found fallopian tube disease and endometriosis(36.01%) ,the rate was 12.14% in another three groups,there were statistical difference. The rate of clinical pregnancy following three cycles intrauterine insemination was 7.67%,it was lower than the cycles less two times intrauterine insemination. The rate of clinical pregnancy in IVF group was significantly higher than in other groups. Conclusion IUI were not suggested more than two cycles,if not succeeded,infertility factor should be analyzed,and the other method should be employed.