Effects of Levonorgestrel-Releasing Intrauterine System on Menstrual Patterns of Patients with Adenomyosis

Objective To explore the variation of menstrual patterns of patients who suffered from adenomyosis after the treatment with levonorgestrel via intrauterine releasing system.Methods Seventy patients with adenomyosis who were inserted with levonorgestrel-releasing intrauterine system were selected.The variation of menstrual patterns was assessed through menstrual blood loss method and dysmenorrhea scoring at beginning and 1,3,6,9 months after insertion.Results Sixty-five patients completed follow-up,which accounted for 92.9%.Menstrual blood volume of baseline and 1,3,6,9 months after therapy was(193.03±134.79),(21.08±32.13),(5.56±7.16),(2.13±4.28),(1.51±2.89),respectively.Compared to the baseline,the menstrual blood volume and blood clot of the patients were significantly decreased at 1,3,6,9 months after treatment.The dysmenorrhea score of 27 patients at the same time point was 1.85±0.82(prior-insertion),0.48±0.51(one month post-insertion),0.13±0.34(three months post-insertion),0(six months post-insertion),respectively,and the dysmenorrheal normally occurred after vaginal ring operation was obviously relieved after insertion.Conclusion Levonorgestrel-releasing intrauterine system displays good therapeutic effect on improving the menstrual patterns of patients with adenomyosis.