Adenomyosis and chronic endometritis: cause, consequence or coincidence? A systematic review and meta-analysis.

Marcel Steinmann, Dimitrios Rafail Kalaitzopoulos, Alexandra Kohl Schwartz, Tanya Karrer, Michael von Wolff, Angela Vidal
2026 · doi:10.48620/97904 · W7161846768
article OA: green CC0
🔓 Open OA copy Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This systematic review and meta-analysis found a pooled prevalence of 32% for chronic endometritis in women with adenomyosis, indicating they frequently coexist with a significantly higher risk of endometritis in those with adenomyosis.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-24 · read from full text ⓘ

I can’t access the paper content because the provided text is blocked by a Proof-of-Work/anti-scraping page (“Making sure you're not a bot!”), so I’m unable to summarize the study’s methods, findings, or stated limitations from the actual article. Based on the title alone, the work is described as a systematic review and meta-analysis evaluating whether adenomyosis and chronic endometritis are causally related, consequential, or merely coincident. This paper is centrally about endometriosis and/or adenomyosis — adenomyosis is explicitly targeted in the title alongside chronic endometritis, even though the specific endometriosis/adenomyosis evidence cannot be verified from the inaccessible content.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Chronic endometritis is persistent inflammation of the endometrium, often underdiagnosed due to its oligosymptomatic presentation. Both chronic endometritis and adenomyosis share inflammatory and structural alterations of the endometrial-myometrial interface that may impair reproductive outcomes. This systematic review and meta-analysis were conducted in accordance with the PRISMA guidelines, and registered in PROSPERO. MEDLINE, Embase, CENTRAL, Cochrane Database of Systematic Reviews, Scopus and trial registries were searched from 2000 to May 2025 to determine the prevalence of chronic endometritis in women with adenomyosis, and assess the strength of their association. Of 713 identified records, 10 studies (n = 2877 women) met the inclusion criteria. The pooled prevalence of chronic endometritis in women with adenomyosis was 32% (95% CI 16-53; I² = 94%). In subgroup analyses, prevalence varied by the diagnostic method used for adenomyosis: hysterectomy (21%), magnetic resonance imaging (64%), and hysteroscopy (8%). Meta-analysis demonstrated a significantly higher prevalence of chronic endometritis in women with adenomyosis compared with controls (OR = 3.81, 95% CI 2.23-6.50; I² = 11%). This systematic review and meta-analysis suggest that adenomyosis and chronic endometritis frequently coexist, with women with adenomyosis showing a significantly higher risk of chronic endometritis. Standardized diagnostic criteria, adenomyosis subtype classification, and high-quality randomized controlled trials are needed to clarify the underlying mechanisms, and are necessary to demonstrate an association between adenomyosis and chronic endometritis.
Full text 1,068 characters · extracted from oa-html · click to expand
Making sure you're not a bot! Loading... You are seeing this because the administrator of this website has set up Anubis to protect the server against the scourge of AI companies aggressively scraping websites. This can and does cause downtime for the websites, which makes their resources inaccessible for everyone. Anubis is a compromise. Anubis uses a Proof-of-Work scheme in the vein of Hashcash, a proposed proof-of-work scheme for reducing email spam. The idea is that at individual scales the additional load is ignorable, but at mass scraper levels it adds up and makes scraping much more expensive. Ultimately, this is a placeholder solution so that more time can be spent on fingerprinting and identifying headless browsers (EG: via how they do font rendering) so that the challenge proof of work page doesn't need to be presented to users that are much more likely to be legitimate. Please note that Anubis requires the use of modern JavaScript features that plugins like JShelter will disable. Please disable JShelter or other such plugins for this domain.

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-html ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

adenomyosis

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. This is a recent paper (2026) — citers typically take a year or two to land, and the OpenAlex reference graph may still be filling in.

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK